Complement C2

BE0012547ProteinHumansC2

Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens... It is acted on by 1 drug in DrugBank.

Gene name
C2
UniProtKB entry
P06681Swiss-Prot
Cellular location
Secreted
Residues / weight
752 residues · 83,267 Da
Also known as
C3/C5 convertase

Resolves to

Protein
UniProtP06681UniProt nameCO2_HUMAN
Gene
HGNCHGNC:1248NCBI Gene717GeneCardsC2
Pharmacology
KEGGhsa:717
Structure
PDB2I6QPDB2I6SPDB2ODP
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Complement C2, and which indications are they being tested in?

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