Empasiprubart

Identification

Generic Name
Empasiprubart
DrugBank Accession Number
DB16469
Background

Empasiprubart is a humanized sweeping antibody designed to bind to C2, a protein in the complement cascade that leads to cell destruction when activated.2

Type
Biotech
Groups
Investigational
Synonyms
  • Empasiprubart
External IDs
  • ARGX-117

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action

ARGX-117 binds to and inhibits the function of the C2 protein, and subsequently, its complement activation. This compound has the potential to augment inflammation and associated adaptive immune responses, which may aid in autoimmunity effects.

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
PVA73UA67L
CAS number
2579031-19-7

References

General References
  1. External Link [Link]
  2. argenx: Empasiprubart [Link]
Not Available

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
2Active Not RecruitingTreatmentMultifocal Motor Neuropathy (MMN)1somestatusstop reasonjust information to hide
2Not Yet RecruitingTreatmentDermatomyositis (DM) / Inflammation;Muscle(S)1somestatusstop reasonjust information to hide
2RecruitingTreatmentDelayed Graft Function1somestatusstop reasonjust information to hide
2RecruitingTreatmentMultifocal Motor Neuropathy (MMN)1somestatusstop reasonjust information to hide
1CompletedOtherHealthy Volunteers (HV)1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at January 21, 2021 01:43 / Updated at June 27, 2024 01:28