Kallikrein-2

BE0012874ProteinHumansKLK2

Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. It is acted on by 2 drugs in DrugBank.

Gene name
KLK2
UniProtKB entry
P20151Swiss-Prot
Residues / weight
261 residues · 28,671 Da
Also known as
3.4.21.35 · Glandular kallikrein-1 · hGK-1 · Tissue kallikrein-2

Resolves to

Protein
UniProtP20151UniProt nameKLK2_HUMAN
Gene
HGNCHGNC:6363NCBI Gene3817GeneCardsKLK2
Pharmacology
IUPHAR/GtoPdb2372KEGGhsa:3817
Structure
PDB4NFEPDB4NFF
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Kallikrein-2, and which indications are they being tested in?

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