Ketohexokinase

BE0013325ProteinHumansKHK

Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate. It is acted on by 1 drug in DrugBank.

Gene name
KHK
UniProtKB entry
P50053Swiss-Prot
Residues / weight
298 residues · 32,523 Da
Also known as
2.7.1.3 · Hepatic fructokinase

Resolves to

Protein
UniProtP50053UniProt nameKHK_HUMAN
Gene
HGNCHGNC:6315NCBI Gene3795GeneCardsKHK
Pharmacology
IUPHAR/GtoPdb3236KEGGhsa:3795
Structure
PDB2HLZPDB2HQQPDB2HW1
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Ketohexokinase, and which indications are they being tested in?

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