C-C chemokine receptor type 8

BE0013343ProteinHumansCCR8

G protein-coupled receptor that can bind a variety of chemokines, such as CCL1, CCL8, CCL16, CCL18 (PubMed:23999500, PubMed:35041514). It is acted on by 2 drugs in DrugBank.

Gene name
CCR8
UniProtKB entry
P51685Swiss-Prot
Cellular location
Cell membrane
Residues / weight
355 residues · 40,844 Da
Also known as
C-C CKR-8 · CC chemokine receptor CHEMR1 · CC-CKR-8 · CCR-8 · Chemokine receptor-like 1

Resolves to

Protein
UniProtP51685UniProt nameCCR8_HUMAN
Gene
HGNCHGNC:1609NCBI Gene1237GeneCardsCCR8
Pharmacology
IUPHAR/GtoPdb65KEGGhsa:1237
Structure
PDB8KFXPDB8KFYPDB8KFZ
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on C-C chemokine receptor type 8, and which indications are they being tested in?

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