Nuclear cap-binding protein subunit 2

BE0013483ProteinHumansNCBP2

Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by... It is acted on by 1 drug in DrugBank.

Gene name
NCBP2
UniProtKB entry
P52298Swiss-Prot
Cellular location
Nucleus
Residues / weight
156 residues · 18,001 Da
Also known as
20 kDa nuclear cap-binding protein · CBP20 · Cell proliferation-inducing gene 55 protein · NCBP 20 kDa subunit · NCBP-interacting protein 1

Resolves to

Protein
UniProtP52298UniProt nameNCBP2_HUMAN
Gene
HGNCHGNC:7659NCBI Gene22916GeneCardsNCBP2
Pharmacology
KEGGhsa:22916
Structure
PDB1H2TPDB1H2UPDB1H2V
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Nuclear cap-binding protein subunit 2, and which indications are they being tested in?

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