Trifunctional enzyme subunit beta, mitochondrial

BE0013748ProteinHumansHADHB

Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway (PubMed:1550553, PubMed:16423905, PubMed:26474213, PubMed:29915090, PubMed:30850536, PubMed:8135828). It is acted on by 1 drug in DrugBank.

Gene name
HADHB
UniProtKB entry
P55084Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
474 residues · 51,294 Da
Also known as
TP-beta

Resolves to

Protein
UniProtP55084UniProt nameECHB_HUMAN
Gene
HGNCHGNC:4803NCBI Gene3032GeneCardsHADHB
Pharmacology
KEGGhsa:3032
Structure
PDB5ZQZPDB5ZRVPDB6DV2
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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17GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Trifunctional enzyme subunit beta, mitochondrial, and which indications are they being tested in?

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