Ninerafaxstat

DB21486InvestigationalSmall molecule

Ninerafaxstat is a small molecule drug. Ninerafaxstat is under investigation in clinical trial NCT07023614 (A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic... Ninerafaxstat has a monoisotopic molecular weight of 415.21 Da.

Mechanism: Pharmacologically active on Trifunctional enzyme subunit beta, mitochondrial
Curator reviewed
Formula / weight: C₂₂H₂₉N₃O₅ · 415.49 g/mol (avg)
Code names: IMB-1018972

Resolves to

Compound

UNII0RB6V4E5XNCAS2254741-41-6ChEMBLCHEMBL5095242ChEBI758819PubChem137359209

Structure

InChIKeyAGVJLPKGBKSLKF-UHFFFAOYSA-NSMILESCOC1=C(OC)C(OC)=C(CN2CCN(CCOC(=O)C3=CC=CN=C3)CC2)C=C1

Targets

P55084HADHB

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with Ninerafaxstat, and which of those have an active Phase 3 trial?

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