Interleukin-1 receptor-like 1

BE0013861ProteinHumansIL1RL1

Receptor for interleukin-33 (IL-33) which plays crucial roles in innate and adaptive immunity, contributing to tissue homeostasis and responses to environmental stresses together with coreceptor IL1RAP (PubMed:35238669). It is acted on by 3 drugs in DrugBank.

Gene name
IL1RL1
UniProtKB entry
Q01638Swiss-Prot
Cellular location
Cell membrane
Residues / weight
556 residues · 63,357 Da
Also known as
3.2.2.6 · DER4 · Protein ST2 · ST2 · T1

Resolves to

Protein
UniProtQ01638UniProt nameILRL1_HUMAN
Gene
HGNCHGNC:5998NCBI Gene9173GeneCardsIL1RL1
Pharmacology
KEGGhsa:9173
Structure
PDB4KC3
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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21GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Interleukin-1 receptor-like 1, and which indications are they being tested in?

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