Astegolimab

DB16386InvestigationalProtein Based Therapies

Astegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).

Mechanism: Pharmacologically active on Interleukin-1 receptor-like 1
Curator reviewed
Code names: AMG-282 · MSTT-1041A · RG-6149 · RO-7187807 · WHO 11067

Resolves to

Compound

UNII27TW751DTHCAS2173054-79-8

Targets

Q01638IL1RL1

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

9Clinical trialsPhase, status and sponsor resolved per trial

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Astegolimab, and which of those have an active Phase 3 trial?

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