Transcription factor Spi-B

BE0013918ProteinHumansSPIB

Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. It is acted on by 2 drugs in DrugBank.

Gene name
SPIB
UniProtKB entry
Q01892Swiss-Prot
Cellular location
Nucleus
Residues / weight
262 residues · 28,818 Da

Resolves to

Protein
UniProtQ01892UniProt nameSPIB_HUMAN
Gene
HGNCHGNC:11242NCBI Gene6689GeneCardsSPIB
Pharmacology
KEGGhsa:6689
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Transcription factor Spi-B, and which indications are they being tested in?

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