Alpha-(1,3)-fucosyltransferase 7

BE0014260ProteinHumansFUT7

Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine unit of a glycoprotein or a glycolipid-linked sialopolylactosamines chain through an alpha-1,3 glycosidic linkage and... It is acted on by 1 drug in DrugBank.

Gene name
FUT7
UniProtKB entry
Q11130Swiss-Prot
Cellular location
Golgi apparatus, Golgi stack membrane
Residues / weight
342 residues · 39,238 Da
Also known as
2.4.1.- · Fuc-TVII · Fucosyltransferase 7 · Fucosyltransferase VII · FucT-VII

Resolves to

Protein
UniProtQ11130UniProt nameFUT7_HUMAN
Gene
HGNCHGNC:4018NCBI Gene2529GeneCardsFUT7
Pharmacology
KEGGhsa:2529
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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27GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Alpha-(1,3)-fucosyltransferase 7, and which indications are they being tested in?

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