StAR-related lipid transfer protein 3

BE0014576ProteinHumansSTARD3

Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes (PubMed:11053434, PubMed:15930133, PubMed:22514632, PubMed:28377464, PubMed:33124732). It is acted on by 1 drug in DrugBank.

Gene name
STARD3
UniProtKB entry
Q14849Swiss-Prot
Cellular location
Late endosome membrane
Residues / weight
445 residues · 50,502 Da
Also known as
CAB1 · Metastatic lymph node gene 64 protein · MLN 64 · MLN64 · Protein CAB1

Resolves to

Protein
UniProtQ14849UniProt nameSTAR3_HUMAN
Gene
HGNCHGNC:17579NCBI Gene10948GeneCardsSTARD3
Pharmacology
KEGGhsa:10948
Structure
PDB1EM2PDB5I9JPDB6TQR
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on StAR-related lipid transfer protein 3, how selective are they, and which programs against it are still in active trials?

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