Lysosome membrane protein 2

BE0014604ProteinHumansSCARB2

Acts as a lysosomal receptor for glucosylceramidase (GBA1) targeting. It is acted on by 1 drug in DrugBank.

Gene name
SCARB2
UniProtKB entry
Q14108Swiss-Prot
Cellular location
Lysosome membrane
Residues / weight
478 residues · 54,290 Da
Also known as
85 kDa lysosomal membrane sialoglycoprotein · CD36 antigen-like 2 · CD36L2 · LGP85 · LIMP II

Resolves to

Protein
UniProtQ14108UniProt nameSCRB2_HUMAN
Gene
HGNCHGNC:1665NCBI Gene950GeneCardsSCARB2
Pharmacology
KEGGhsa:950
Structure
PDB4F7BPDB4Q4BPDB4Q4F
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Lysosome membrane protein 2, how selective are they, and which programs against it are still in active trials?

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