Zeaxanthin

DB11176ApprovedInvestigationalSmall molecule

Zeaxanthin is a most common carotenoid alcohols found in nature that is involved in the xanthophyll cycle. As a coexistent isomer of lutein, zeaxanthin is synthesized in plants and some... It gives the distinct yellow color to many vegetables and other plants including paprika, corn, saffron and wolfberries.

Mechanism: Pharmacologically active on Glutathione S-transferase P
Curator reviewed
Formula / weight: C₄₀H₅₆O₂ · 568.886 g/mol (avg)
Code names: E 161H · E-161H(I) · INS-161H(I) · INS NO.161H(I)

Resolves to

Compound

UNIICV0IB81OROCAS144-68-3ChEMBLCHEMBL2359248ChEBI27547PubChem5280899KEGGC06098

Clinical / RWD

RxNorm39918

Structure

InChIKeyJKQXZKUSFCKOGQ-QAYBQHTQSA-NSMILESC\C(\C=C\C=C(/C)\C=C\C1=C(C)C[C@@H](O)CC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C

Targets

P09211GSTP1

Transporters

Q8WTV0SCARB1P16671CD36Q14108SCARB2

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3TransportersSubstrate / inhibitor direction, not just membership

Listed above

9Clinical trialsPhase, status and sponsor resolved per trial

3Structured indicationsCondition, population, route and combination as fields, not prose

13Marketed productsAcross 3 countries and 10 labellers

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Zeaxanthin, and which of those have an active Phase 3 trial?

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