Potassium channel subfamily T member 1

BE0015369ProteinHumansKCNT1

Sodium-activated K(+) channel (PubMed:37494189). It is acted on by 4 drugs in DrugBank.

Gene name
KCNT1
UniProtKB entry
Q5JUK3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,230 residues · 138,342 Da
Also known as
KCa4.1 · KIAA1422 · KNa1.1 · SLACK · Slo2.2

Resolves to

Protein
UniProtQ5JUK3UniProt nameKCNT1_HUMAN
Gene
HGNCHGNC:18865NCBI Gene57582GeneCardsKCNT1
Pharmacology
IUPHAR/GtoPdb385KEGGhsa:57582
Structure
PDB8HIRPDB8HK6PDB8HKF
Drugs

What you can answer from here — as of September 03, 2024

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium channel subfamily T member 1, how selective are they, and which programs against it are still in active trials?

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