Potassium channel subfamily T member 2

BE0015626ProteinHumansKCNT2

Sodium-activated and chloride-activated potassium channel (PubMed:14684870, PubMed:16687497, PubMed:25214519, PubMed:27682982, PubMed:29069600, PubMed:29740868). It is acted on by 2 drugs in DrugBank.

Gene name
KCNT2
UniProtKB entry
Q6UVM3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,135 residues · 130,500 Da
Also known as
KNa1.2 · Sequence like an intermediate conductance potassium channel subunit · SLICK · Slo2.1 · Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1

Resolves to

Protein
UniProtQ6UVM3UniProt nameKCNT2_HUMAN
Gene
HGNCHGNC:18866NCBI Gene343450GeneCardsKCNT2
Pharmacology
IUPHAR/GtoPdb386KEGGhsa:343450
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
6GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Potassium channel subfamily T member 2, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In