Potassium channel subfamily T member 2

BE0015626ProteinHumansKCNT2

Sodium-activated and chloride-activated potassium channel (PubMed:14684870, PubMed:16687497, PubMed:25214519, PubMed:27682982, PubMed:29069600, PubMed:29740868). It is acted on by 2 drugs in DrugBank.

Gene name
KCNT2
UniProtKB entry
Q6UVM3Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,135 residues · 130,500 Da
Also known as
KNa1.2 · Sequence like an intermediate conductance potassium channel subunit · SLICK · Slo2.1 · Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1

Resolves to

Protein
UniProtQ6UVM3UniProt nameKCNT2_HUMAN
Gene
HGNCHGNC:18866NCBI Gene343450GeneCardsKCNT2
Pharmacology
IUPHAR/GtoPdb386KEGGhsa:343450
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Potassium channel subfamily T member 2, and which indications are they being tested in?

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