Lysophosphatidylcholine acyltransferase 2

BE0016122ProteinHumansLPCAT2

Exhibits both acyltransferase and acetyltransferase activities (PubMed:17182612, PubMed:20363836, PubMed:21498505). It is acted on by 3 drugs in DrugBank.

Gene name
LPCAT2
UniProtKB entry
Q7L5N7Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
544 residues · 60,207 Da
Also known as
1-acylglycerol-3-phosphate O-acyltransferase 11 · 1-acylglycerophosphocholine O-acyltransferase · 1-AGP acyltransferase 11 · 1-AGPAT 11 · 1-alkenylglycerophosphocholine O-acyltransferase

Resolves to

Protein
UniProtQ7L5N7UniProt namePCAT2_HUMAN
Gene
HGNCHGNC:26032NCBI Gene54947GeneCardsLPCAT2
Pharmacology
KEGGhsa:54947
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Lysophosphatidylcholine acyltransferase 2, and which indications are they being tested in?

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