Lysophosphatidylcholine acyltransferase 1

BE0017259ProteinHumansLPCAT1

Exhibits acyltransferase activity (PubMed:18156367, PubMed:21498505). It is acted on by 4 drugs in DrugBank.

Gene name
LPCAT1
UniProtKB entry
Q8NF37Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
534 residues · 59,151 Da
Also known as
1-acylglycerol-3-phosphate O-acyltransferase · 1-acylglycerophosphocholine O-acyltransferase · 1-alkenylglycerophosphocholine O-acyltransferase · 1-alkylglycerophosphocholine O-acetyltransferase · 2.3.1.23

Resolves to

Protein
UniProtQ8NF37UniProt namePCAT1_HUMAN
Gene
HGNCHGNC:25718NCBI Gene79888GeneCardsLPCAT1
Pharmacology
KEGGhsa:79888
Drugs

What you can answer from here — as of September 03, 2024

4DrugsApproved to experimental, with action, bond type and pharmacological action
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20GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Lysophosphatidylcholine acyltransferase 1, how selective are they, and which programs against it are still in active trials?

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