Bifunctional FAD diphosphatase/FAD synthase

BE0017310ProteinHumansFLAD1

This enzyme has two activities: FAD diphosphatase activity and FAD synthase activity (PubMed:16643857, PubMed:21924249, PubMed:21951714, PubMed:23443125, PubMed:25135855, PubMed:26277395, PubMed:27259049, PubMed:31351152, PubMed:38688286). It is acted on by 1 drug in DrugBank.

Gene name
FLAD1
UniProtKB entry
Q8NFF5Swiss-Prot
Cellular location
Nucleus
Residues / weight
587 residues · 65,265 Da

Resolves to

Protein
UniProtQ8NFF5UniProt nameFAD1_HUMAN
Gene
HGNCHGNC:24671NCBI Gene80308GeneCardsFLAD1
Pharmacology
KEGGhsa:80308
Structure
PDB8ROMPDB8RON
Drugs

What you can answer from here — as of June 05, 2026

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
1Metabolic reactionDrug transformations it catalyses, substrate to product
Sign in
10GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which approved drugs act on Bifunctional FAD diphosphatase/FAD synthase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In