Sodium/myo-inositol cotransporter 2

BE0017647ProteinHumansSLC5A11

Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1 (PubMed:15172003, PubMed:19032932). It is acted on by 1 drug in DrugBank.

Gene name
SLC5A11
UniProtKB entry
Q8WWX8Swiss-Prot
Cellular location
Membrane
Residues / weight
675 residues · 74,036 Da
Also known as
KST1 · Na(+)/myo-inositol cotransporter 2 · SLGTX · SMIT2 · Sodium-dependent glucose cotransporter

Resolves to

Protein
UniProtQ8WWX8UniProt nameSC5AB_HUMAN
Gene
HGNCHGNC:23091NCBI Gene115584GeneCardsSLC5A11
Pharmacology
IUPHAR/GtoPdb925KEGGhsa:115584
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Sodium/myo-inositol cotransporter 2, and which indications are they being tested in?

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