Carnitine O-palmitoyltransferase 1, muscle isoform

Details

Name
Carnitine O-palmitoyltransferase 1, muscle isoform
Kind
protein
Synonyms
  • 2.3.1.21
  • Carnitine O-palmitoyltransferase I, muscle isoform
  • Carnitine palmitoyltransferase 1B
  • Carnitine palmitoyltransferase I-like protein
  • CPT I
  • CPT1-M
  • CPTI-M
  • KIAA1670
Gene Name
CPT1B
UniProtKB Entry
Q92523Swiss-Prot
Organism
Humans
NCBI Taxonomy ID
9606
Amino acid sequence
>lcl|BSEQ0009816|Carnitine O-palmitoyltransferase 1, muscle isoform
MAEAHQAVAFQFTVTPDGVDFRLSREALKHVYLSGINSWKKRLIRIKNGILRGVYPGSPT
SWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWVTG
IFFFRQTLKLLLCYHGWMFEMHGKTSNLTRIWAMCIRLLSSRHPMLYSFQTSLPKLPVPR
VSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEE
YIYLRGRSPLMVNSNYYVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALG
IVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSRHVAVYHKGRFFKLWLYEGARLLKPQDL
EMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVA
LDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPI
IGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAPPTRLQWDIPKQCQAVIESSYQVAKAL
ADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREG
RTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCL
YLVSKYLGVSSPFLAEVLSEPWRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGY
GVSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQVPKAYS
Number of residues
772
Molecular Weight
87800.385
Theoretical pI
Not Available
GO Classification
Not Available
General Function
Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion
Specific Function
carnitine O-palmitoyltransferase activity
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
48-73 103-122
Cellular Location
Mitochondrion outer membrane
Gene sequence
Not Available
Chromosome Location
22
Locus
22q13.33
External Identifiers
ResourceLink
UniProtKB IDQ92523
UniProtKB Entry NameCPT1B_HUMAN
GeneCard IDCPT1B
HGNC IDHGNC:2329
KEGG IDhsa:1375
NCBI Gene ID1375
General References
Not Available

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Perhexilineapproved, investigationalyestargetinhibitorDetails
Levocarnitineapproved, investigationalyestargetactivatorDetails