Carnitine O-palmitoyltransferase 1, muscle isoform
Details
- Name
- Carnitine O-palmitoyltransferase 1, muscle isoform
- Kind
- protein
- Synonyms
- 2.3.1.21
- Carnitine O-palmitoyltransferase I, muscle isoform
- Carnitine palmitoyltransferase 1B
- Carnitine palmitoyltransferase I-like protein
- CPT I
- CPT1-M
- CPTI-M
- KIAA1670
- Gene Name
- CPT1B
- UniProtKB Entry
- Q92523Swiss-Prot
- Organism
- Humans
- NCBI Taxonomy ID
- 9606
- Amino acid sequence
>lcl|BSEQ0009816|Carnitine O-palmitoyltransferase 1, muscle isoform MAEAHQAVAFQFTVTPDGVDFRLSREALKHVYLSGINSWKKRLIRIKNGILRGVYPGSPT SWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWVTG IFFFRQTLKLLLCYHGWMFEMHGKTSNLTRIWAMCIRLLSSRHPMLYSFQTSLPKLPVPR VSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEE YIYLRGRSPLMVNSNYYVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALG IVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSRHVAVYHKGRFFKLWLYEGARLLKPQDL EMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVA LDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPI IGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAPPTRLQWDIPKQCQAVIESSYQVAKAL ADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREG RTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCL YLVSKYLGVSSPFLAEVLSEPWRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGY GVSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQVPKAYS
- Number of residues
- 772
- Molecular Weight
- 87800.385
- Theoretical pI
- Not Available
- GO Classification
- Not Available
- General Function
- Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion
- Specific Function
- carnitine O-palmitoyltransferase activity
- Pfam Domain Function
- Signal Regions
- Not Available
- Transmembrane Regions
- 48-73 103-122
- Cellular Location
- Mitochondrion outer membrane
- Gene sequence
- Not Available
- Chromosome Location
- 22
- Locus
- 22q13.33
- External Identifiers
Resource Link UniProtKB ID Q92523 UniProtKB Entry Name CPT1B_HUMAN GeneCard ID CPT1B HGNC ID HGNC:2329 KEGG ID hsa:1375 NCBI Gene ID 1375 - General References
- Not Available
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Perhexiline approved, investigational yes target inhibitor Details Levocarnitine approved, investigational yes target activator Details