Beta-Ala-His dipeptidase

BE0018275ProteinHumansCNDP1

Catalyzes the peptide bond hydrolysis in Xaa-His dipeptides, displaying the highest activity toward carnosine (beta-alanyl-L-histidine). It is acted on by 1 drug in DrugBank.

Gene name
CNDP1
UniProtKB entry
Q96KN2Swiss-Prot
Cellular location
Secreted
Residues / weight
507 residues · 56,692 Da
Also known as
3.4.13.20 · Carnosine dipeptidase 1 · CN1 · CNDP dipeptidase 1 · CPGL2

Resolves to

Protein
UniProtQ96KN2UniProt nameCNDP1_HUMAN
Gene
HGNCHGNC:20675NCBI Gene84735GeneCardsCNDP1
Pharmacology
KEGGhsa:84735
Structure
PDB3DLJ
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Beta-Ala-His dipeptidase, and which indications are they being tested in?

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