Carnosine
Star1
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Carnosine
- DrugBank Accession Number
- DB11695
- Background
Carnosine has been investigated for the treatment of Gulf War Illness.
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 226.2325
Monoisotopic: 226.106590334 - Chemical Formula
- C9H14N4O3
- Synonyms
- L-Carnosine
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key Carnosine Hydrochloride 5II09M0I3L 5852-99-3 HIXYEIRACBUSON-FJXQXJEOSA-N Carnosine Nitrate 1059P8M705 5852-98-2 CPZFLUMGMDPGIE-FJXQXJEOSA-N
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Peptidomimetics
- Sub Class
- Hybrid peptides
- Direct Parent
- Hybrid peptides
- Alternative Parents
- Histidine and derivatives / N-acyl-L-alpha-amino acids / Beta amino acids and derivatives / Imidazolyl carboxylic acids and derivatives / Heteroaromatic compounds / Secondary carboxylic acid amides / Amino acids / Monocarboxylic acids and derivatives / Carboxylic acids / Azacyclic compounds show 5 more
- Substituents
- Alpha-amino acid or derivatives / Amine / Amino acid / Amino acid or derivatives / Aromatic heteromonocyclic compound / Azacycle / Azole / Beta amino acid or derivatives / Carbonyl group / Carboxamide group show 22 more
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- dipeptide (CHEBI:15727)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 8HO6PVN24W
- CAS number
- 305-84-0
- InChI Key
- CQOVPNPJLQNMDC-ZETCQYMHSA-N
- InChI
- InChI=1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1
- IUPAC Name
- (2S)-2-(3-aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid
- SMILES
- NCCC(=O)N[C@@H](CC1=CN=CN1)C(O)=O
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0000033
- KEGG Compound
- C00386
- PubChem Compound
- 439224
- PubChem Substance
- 347828060
- ChemSpider
- 388363
- 1362697
- ChEBI
- 15727
- ChEMBL
- CHEMBL242948
- ZINC
- ZINC000002040854
- PDBe Ligand
- 8V0
- Wikipedia
- Carnosine
- PDB Entries
- 5yf1
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample dataNot Available Completed Treatment Bipolar 1 Disorder 1 somestatus stop reason just information to hide Not Available Completed Treatment Schizoaffective Disorders / Schizophrenia 1 somestatus stop reason just information to hide 4 Unknown Status Treatment Gastro-esophageal Reflux Disease (GERD) 1 somestatus stop reason just information to hide 2 Completed Treatment Gulf War Syndrome 1 somestatus stop reason just information to hide 2 Completed Treatment Peripheral Arterial Disease (PAD) 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 11.1 mg/mL ALOGPS logP -3 ALOGPS logP -4.5 Chemaxon logS -1.3 ALOGPS pKa (Strongest Acidic) 3.37 Chemaxon pKa (Strongest Basic) 9.13 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 121.1 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 55.56 m3·mol-1 Chemaxon Polarizability 22.37 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 154.6571571 predictedDarkChem Lite v0.1.0 [M-H]- 152.9264891 predictedDarkChem Standard v0.1.0 [M-H]- 154.7037571 predictedDarkChem Lite v0.1.0 [M-H]- 145.72902 predictedDeepCCS 1.0 (2019) [M+H]+ 155.3811571 predictedDarkChem Lite v0.1.0 [M+H]+ 152.290513 predictedDarkChem Standard v0.1.0 [M+H]+ 155.5247571 predictedDarkChem Lite v0.1.0 [M+H]+ 148.08705 predictedDeepCCS 1.0 (2019) [M+Na]+ 154.5424571 predictedDarkChem Lite v0.1.0 [M+Na]+ 154.9663571 predictedDarkChem Lite v0.1.0 [M+Na]+ 154.6587571 predictedDarkChem Lite v0.1.0 [M+Na]+ 154.18022 predictedDeepCCS 1.0 (2019)
Drug created at October 20, 2016 20:40 / Updated at September 28, 2021 21:54