Cytosolic non-specific dipeptidase

BE0018303ProteinHumansCNDP2

Cytosolic metallodipeptidase with broad substrate specificity that catalyzes the hydrolysis of amide bonds in dipeptides and pseudopeptides (PubMed:12473676, PubMed:19346245, PubMed:25964343). It is acted on by 1 drug in DrugBank.

Gene name
CNDP2
UniProtKB entry
Q96KP4Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
475 residues · 52,878 Da
Also known as
3.4.13.18 · CN2 · CNDP dipeptidase 2 · CPGL · Glutamate carboxypeptidase-like protein 1

Resolves to

Protein
UniProtQ96KP4UniProt nameCNDP2_HUMAN
Gene
HGNCHGNC:24437NCBI Gene55748GeneCardsCNDP2
Pharmacology
KEGGhsa:55748
Structure
PDB4RUH
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Cytosolic non-specific dipeptidase, and which indications are they being tested in?

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