Mucin-4

BE0018599ProteinHumansMUC4

Membrane-bound mucin, a family of highly glycosylated proteins that constitute the major component of the mucus, the slimy and viscous secretion covering epithelial surfaces (PubMed:10880978). It is acted on by 1 drug in DrugBank.

Gene name
MUC4
UniProtKB entry
Q99102Swiss-Prot
Cellular location
Cell membrane
Residues / weight
5,412 residues · 542,301 Da
Also known as
Ascites sialoglycoprotein · ASGP · MUC-4 · Pancreatic adenocarcinoma mucin · Testis mucin

Resolves to

Protein
UniProtQ99102UniProt nameMUC4_HUMAN
Gene
HGNCHGNC:7514NCBI Gene4585GeneCardsMUC4
Pharmacology
KEGGhsa:4585
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Mucin-4, how selective are they, and which programs against it are still in active trials?

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