NADPH oxidase 5

BE0018640ProteinHumansNOX5

Calcium-dependent NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor (PubMed:12686516). It is acted on by 1 drug in DrugBank.

Gene name
NOX5
UniProtKB entry
Q96PH1Swiss-Prot
Cellular location
Endoplasmic reticulum
Residues / weight
765 residues · 86,438 Da
Also known as
1.-.-.- · 1.6.3.-

Resolves to

Protein
UniProtQ96PH1UniProt nameNOX5_HUMAN
Gene
HGNCHGNC:14874NCBI Gene79400GeneCardsNOX5
Pharmacology
IUPHAR/GtoPdb3005KEGGhsa:79400
Structure
PDB6SZ5PDB8U7YPDB8U85
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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21GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on NADPH oxidase 5, and which indications are they being tested in?

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