Isuzinaxib
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Isuzinaxib
- DrugBank Accession Number
- DB19109
- Background
Isuzinaxib is under investigation in clinical trial NCT05758896 (Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 279.343
Monoisotopic: 279.137162179 - Chemical Formula
- C17H17N3O
- Synonyms
- 1-(pyridin-2-yl)-3-phenyl-4-propyl-1h-pyrazol-5-ol
- 1h-pyrazol-5-ol, 3-phenyl-4-propyl-1-(2-pyridinyl)-
- 3-phenyl-4-propyl-1-(2-pyridinyl)-1h-pyrazol-5-ol
- 3-phenyl-4-propyl-1-(pyridin-2-yl)-1h-pyrazol-5-ol
- Apx-115 free base
- Ewha-18278 free base
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key Isuzinaxib hydrochloride Q99G5ZE5U5 1395946-75-4 GMFJXGGAGPCRBM-UHFFFAOYSA-N
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- YP664UDC7T
- CAS number
- 1270084-92-8
- InChI Key
- LQKQLKMTJOMCMJ-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H17N3O/c1-2-8-14-16(13-9-4-3-5-10-13)19-20(17(14)21)15-11-6-7-12-18-15/h3-7,9-12,21H,2,8H2,1H3
- IUPAC Name
- SMILES
- CCCC1=C(O)N(N=C1C1=CC=CC=C1)C1=CC=CC=N1
References
- General References
- Not Available
- External Links
- ChemSpider
- 81409261
- ChEMBL
- CHEMBL4650894
Clinical Trials
- Clinical Trials
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Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data2 Completed Treatment Diabetic Nephropathy / Type 2 Diabetes Mellitus 1 somestatus stop reason just information to hide 2 Recruiting Prevention Contrast Induced Acute Kidney Injury 1 somestatus stop reason just information to hide 2 Terminated Treatment Coronavirus Disease 2019 (COVID‑19) 1 somestatus stop reason just information to hide 1 Completed Treatment Healthy Volunteers (HV) / Safety 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at July 04, 2024 15:27 / Updated at July 05, 2024 04:43