Aquaporin-10

BE0018706ProteinHumansAQP10

Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed:11573934, PubMed:12084581, PubMed:21733844, PubMed:23382902, PubMed:30420639). It is acted on by 2 drugs in DrugBank.

Gene name
AQP10
UniProtKB entry
Q96PS8Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
301 residues · 31,763 Da
Also known as
AQP-10 · Aquaglyceroporin-10 · Small intestine aquaporin

Resolves to

Protein
UniProtQ96PS8UniProt nameAQP10_HUMAN
Gene
HGNCHGNC:16029NCBI Gene89872GeneCardsAQP10
Pharmacology
KEGGhsa:89872
Structure
PDB6F7H
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aquaporin-10, how selective are they, and which programs against it are still in active trials?

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