Silicon

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Silicon is a micronutrient indicated in nutritional products to treat or prevent silicon deficiencies.

Generic Name
Silicon
DrugBank Accession Number
DB12982
Background

Silicon is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides).

Type
Small Molecule
Groups
Approved, Investigational
Structure
Thumb
Weight
Average: 28.085
Monoisotopic: 27.976926535
Chemical Formula
Si
Synonyms
  • silicio

Pharmacology

Indication

Not Available

Pharmacology
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Associated Therapies
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
  • Take with food.

Products

Products
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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Silica - Liq 80mg/5mlLiquid80 mg / 5 mLOralPurity Plus Advanced Naturals1996-06-272009-07-14Canada flag
Silicare 5mgCapsule5 mg / capOralHolista Health (Canada) Inc.1996-11-192001-08-01Canada flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Actical Plus Calcium-magnesium-vitamin D3-silicon ChewableSilicon (2 mg) + Calcium (200 mg) + Cholecalciferol (100 unit) + Magnesium (100 mg)TabletOralUsana Health Sciences, Inc.1999-09-302004-07-27Canada flag
Active Calcium Plus Magnesium, Vitamin D and SiliconSilicon (2.25 mg) + Calcium (200 mg) + Cholecalciferol (100 unit) + Magnesium (100 mg)TabletOralUsana Health Sciences, Inc.2002-07-082007-07-18Canada flag
Advanced B & T FormulaSilicon (0.333 mg) + Ascorbic acid (33.3 mg) + Calcium (200 mg) + Chromium (33.33 mcg) + Copper (0.5 mg) + Cyanocobalamin (6.67 mcg) + Folic acid (0.133 mg) + Iron (1.67 mg) + Magnesium (83.3 mg) + Manganese (3.33 mg) + Nicotinamide (6.67 mg) + Calcium pantothenate (5 mg) + Phosphorus (100 mg) + Potassium (16.67 mg) + Pyridoxine hydrochloride (6.67 mg) + Riboflavin (2.67 mg) + Selenium (33.33 mcg) + Sodium molybdate (16.67 mcg) + Thiamine (2.67 mg) + Vanadium (8.33 mg) + Vitamin D (66.67 unit) + Zinc (5 mg)CapsuleOralNutraceutical CorporationNot applicableNot applicableCanada flag
Body RoxSilicon (1.0 mg) + Beta carotene (3000.0 unit) + Biotin (100.0 mcg) + Calcium (75.0 mg) + Calcium ascorbate (167.0 mg) + Cholecalciferol (133.0 unit) + Choline bitartrate (15.0 mg) + Chromium (50.0 mcg) + Copper (0.33 mg) + Cyanocobalamin (20.0 mcg) + Folic acid (0.267 mg) + Inositol (10.0 mg) + Magnesium (37.5 mg) + Manganese (1.0 mg) + Molybdenum (15.0 mcg) + Niacin (1.66 mg) + Nicotinamide (3.3 mg) + Calcium pantothenate (10.0 mg) + Potassium Iodide (0.05 mg) + Pyridoxine hydrochloride (3.0 mg) + Riboflavin (3.0 mg) + Selenium (40.0 mcg) + Thiamine hydrochloride (3.0 mg) + Vanadium (10.0 mcg) + Zinc (4.0 mg) + alpha-Tocopherol succinate (66.7 unit)TabletOralUsana Health Sciences, Inc.2003-09-022008-06-27Canada flag
C. Vit-min FormulaSilicon (0.01 mg) + Ascorbic acid (100 mg) + Biotin (30 mcg) + Calcium (175 mg) + Cholecalciferol (400 unit) + Choline (30 mg) + Chromium (50 mcg) + Copper (5 mg) + Cyanocobalamin (100 mcg) + Ferrous fumarate (10 mg) + Folic acid (0.600 mg) + Inositol (30 mg) + Magnesium (80 mg) + Manganese (5 mg) + Molybdenum (25 mcg) + Nicotinamide (50 mg) + Calcium pantothenate (50 mg) + Potassium (40 mg) + Potassium Iodide (0.15 mg) + Pyridoxine hydrochloride (50 mg) + Racemethionine (3 mg) + Riboflavin (50 mg) + Sodium selenite (200 mcg) + Thiamine (50 mg) + Vanadium (10 mcg) + Vitamin A (5000 unit) + Zinc (40 mg) + alpha-Tocopherol acetate (100 unit)TabletOralNutramed Laboratories Inc.Not applicableNot applicableCanada flag
Calcium Complex High GradeSilicon (1 mg) + Ascorbic acid (33 mg) + Calcium (200 mg) + Cholecalciferol (66 unit) + Chromium (10 mcg) + Magnesium (83 mg) + Manganese (1 mg) + Zinc (6 mg)CapsuleOralNew Spirit Naturals, Inc.Not applicableNot applicableCanada flag
Calcium Magnesium Sulfur Silicon - TabSilicon (10 mg / tab) + Calcium (250 mg / tab) + Magnesium (125 mg / tab) + Octasulfur (15 mg / tab)TabletOralPro Shop Inc.1995-12-312000-07-31Canada flag
Calcium With Mg Zn Mn Cu CR Si and Vit. C & DSilicon (3.5 mg) + Ascorbic acid (6.6 mg) + Calcium (83.3 mg) + Cholecalciferol (66.7 unit) + Chromium (16.67 mcg) + Copper (.33 mg) + Magnesium (41.67 mg) + Manganese (.83 mg) + Zinc (1.67 mg)TabletOralJamieson Laboratories Ltd1993-12-312001-09-14Canada flag
CalcorSilicon (2 mg) + Calcium (500 mg) + Magnesium (140 mg) + Potassium bicarbonate (100 mg)TabletOralSimone Protective Pharmaceuticals, Inc.Not applicableNot applicableCanada flag
CalplusSilicon (10 mg) + Ascorbic acid (60 mg) + Calcium (500 mg) + Cholecalciferol (100 unit) + Copper (1 mg) + Magnesium (250 mg) + Zinc (5 mg)TabletOralLifestyles Canada Corporation1998-08-072000-07-16Canada flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as homogeneous metalloid compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a metalloid atom.
Kingdom
Inorganic compounds
Super Class
Homogeneous metal compounds
Class
Homogeneous metalloid compounds
Sub Class
Not Available
Direct Parent
Homogeneous metalloid compounds
Alternative Parents
Not Available
Substituents
Homogeneous metalloid
Molecular Framework
Not Available
External Descriptors
nonmetal atom, carbon group element atom (CHEBI:27573)
Affected organisms
Not Available

Chemical Identifiers

UNII
Z4152N8IUI
CAS number
7440-21-3
InChI Key
XUIMIQQOPSSXEZ-UHFFFAOYSA-N
InChI
InChI=1S/Si
IUPAC Name
silicon
SMILES
[Si]

References

General References
Not Available
PubChem Compound
5461123
PubChem Substance
347829121
ChemSpider
4574465
RxNav
9774
ChEBI
27573
Wikipedia
Silicon

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet, film coatedOral
CapsuleOral
TabletOral
CapsuleOral
LiquidOral
LiquidOral80 mg / 5 mL
CapsuleOral5 mg / cap
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0.045ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created on October 21, 2016 01:46 / Updated on July 29, 2021 06:27