Interleukin-12 receptor subunit beta-2

BE0018860ProteinHumansIL12RB2

Receptor for interleukin-12. It is acted on by 5 drugs in DrugBank.

Gene name
IL12RB2
UniProtKB entry
Q99665Swiss-Prot
Cellular location
Membrane
Residues / weight
862 residues · 97,134 Da
Also known as
IL-12 receptor subunit beta-2 · IL-12R subunit beta-2 · IL-12R-beta-2 · IL-12RB2

Resolves to

Protein
UniProtQ99665UniProt nameI12R2_HUMAN
Gene
HGNCHGNC:5972NCBI Gene3595GeneCardsIL12RB2
Pharmacology
KEGGhsa:3595
Structure
PDB8XRPPDB8YI7
Drugs

What you can answer from here — as of September 03, 2024

5DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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19+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Interleukin-12 receptor subunit beta-2, and which indications are they being tested in?

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