MVR-T3011

DB17378InvestigationalGene Therapies

MVR-T3011 is a genetically modified oncolytic Herpes Simplex Virus (HSV-1) with 2 exogenous genes encoding the active heterodimer human interleukin 12 (IL-12) and the Fab fragment of an anti-human PD-1...

Mechanism: Pharmacologically active on Interleukin-12 subunit beta, Programmed cell death protein 1, and Interleukin-12 subunit alpha
Curator reviewed
Also known as: T3011
Code names: MVR-T3011

Resolves to

Targets

P29460IL12BQ15116PDCD1P29459IL12AP42701IL12RB1Q99665IL12RB2

What you can answer from here — as of October 05, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

12Clinical trialsPhase, status and sponsor resolved per trial

20+ReferencesStructured and connected to the statements they support

Which drugs share a target with MVR-T3011, and which of those have an active Phase 3 trial?

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