Testicular acid phosphatase

BE0019349ProteinHumansACP4

Protein tyrosine phosphatase that dephosphorylates the receptor tyrosine-protein kinase ERBB4, thereby inhibiting its ligand-induced proteolytic cleavage (PubMed:15219672). It is acted on by 1 drug in DrugBank.

Gene name
ACP4
UniProtKB entry
Q9BZG2Swiss-Prot
Cellular location
Membrane
Residues / weight
426 residues · 46,089 Da
Also known as
3.1.3.48 · Acid phosphatase 4 · ACPT

Resolves to

Protein
UniProtQ9BZG2UniProt namePPAT_HUMAN
Gene
HGNCHGNC:14376NCBI Gene93650GeneCardsACP4
Pharmacology
KEGGhsa:93650
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Testicular acid phosphatase, how selective are they, and which programs against it are still in active trials?

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