Mucin-5B

BE0019774ProteinHumansMUC5B

Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. It is acted on by 1 drug in DrugBank.

Gene name
MUC5B
UniProtKB entry
Q9HC84Swiss-Prot
Cellular location
Secreted
Residues / weight
5,762 residues · 596,334 Da
Also known as
Cervical mucin · High molecular weight salivary mucin MG1 · MUC-5B · MUC5 · Mucin-5 subtype B, tracheobronchial

Resolves to

Protein
UniProtQ9HC84UniProt nameMUC5B_HUMAN
Gene
HGNCHGNC:7516NCBI Gene727897GeneCardsMUC5B
Pharmacology
KEGGhsa:727897
Structure
PDB8OERPDB8OES
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Mucin-5B, how selective are they, and which programs against it are still in active trials?

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