Taste receptor type 2 member 4

BE0020472ProteinHumansTAS2R4

Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. It is acted on by 2 drugs in DrugBank.

Gene name
TAS2R4
UniProtKB entry
Q9NYW5Swiss-Prot
Cellular location
Membrane
Residues / weight
299 residues · 33,840 Da
Also known as
T2R4

Resolves to

Protein
UniProtQ9NYW5UniProt nameTA2R4_HUMAN
Gene
HGNCHGNC:14911NCBI Gene50832GeneCardsTAS2R4
Pharmacology
IUPHAR/GtoPdb661KEGGhsa:50832
Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Taste receptor type 2 member 4, how selective are they, and which programs against it are still in active trials?

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