Transient receptor potential cation channel subfamily M member 5

BE0020643ProteinHumansTRPM5

Monovalent cation-selective ion channel activated by intracellular Ca(2+) in a voltage- and temperature-dependent manner (PubMed:14634208). It is acted on by 1 drug in DrugBank.

Gene name
TRPM5
UniProtKB entry
Q9NZQ8Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,165 residues · 131,450 Da
Also known as
Long transient receptor potential channel 5 · LTrpC-5 · LTRPC5 · MLSN1- and TRP-related gene 1 protein · MTR1

Resolves to

Protein
UniProtQ9NZQ8UniProt nameTRPM5_HUMAN
Gene
HGNCHGNC:14323NCBI Gene29850GeneCardsTRPM5
Pharmacology
IUPHAR/GtoPdb497KEGGhsa:29850
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which approved drugs act on Transient receptor potential cation channel subfamily M member 5, how selective are they, and which programs against it are still in active trials?

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