Short transient receptor potential channel 4

BE0020751ProteinHumansTRPC4

Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:11042129, PubMed:11713258, PubMed:16144838, PubMed:39478185). It is acted on by 1 drug in DrugBank.

Gene name
TRPC4
UniProtKB entry
Q9UBN4Swiss-Prot
Cellular location
Cell membrane
Residues / weight
977 residues · 112,100 Da
Also known as
hTrp-4 · hTrp4 · Trp-related protein 4 · TrpC4

Resolves to

Protein
UniProtQ9UBN4UniProt nameTRPC4_HUMAN
Gene
HGNCHGNC:12336NCBI Gene7223GeneCardsTRPC4
Pharmacology
IUPHAR/GtoPdb489KEGGhsa:7223
Structure
PDB8WPLPDB8WPMPDB8WPN
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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19GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Short transient receptor potential channel 4, and which indications are they being tested in?

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