Short transient receptor potential channel 6

BE0020965ProteinHumansTRPC6

Non-selective, calcium-permeable cation channel (PubMed:19936226, PubMed:23291369, PubMed:26892346, PubMed:9930701). It is acted on by 2 drugs in DrugBank.

Gene name: TRPC6
UniProtKB entry: Q9Y210Swiss-Prot
Cellular location: Cell membrane
Residues / weight: 931 residues · 106,325 Da
Also known as: Transient receptor protein 6 · TRP-6 · TRP6 · TrpC6

Resolves to

Protein

UniProtQ9Y210UniProt nameTRPC6_HUMAN

Gene

HGNCHGNC:12338NCBI Gene7225GeneCardsTRPC6

Pharmacology

IUPHAR/GtoPdb491KEGGhsa:7225

Structure

PDB5YX9PDB6UZ8PDB6UZA

Drugs

What you can answer from here — as of September 03, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action

3Pfam domainsDomain architecture mapped to Pfam families and clans

2+ReferencesStructured and connected to the statements they support

Which compounds in development act on Short transient receptor potential channel 6, and which indications are they being tested in?

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