SKF-96365 free base

DB17054ExperimentalSmall molecule

SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists.

Mechanism: Pharmacologically active on Transient receptor potential cation channel subfamily M member 8, Transient receptor potential cation channel subfamily V member 2, and Stromal interaction molecule 1
Curator reviewed
Formula / weight: C₂₂H₂₆N₂O₃ · 366.461 g/mol (avg)
Also known as: 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole

Resolves to

Compound

Structure

InChIKeyHLMBXBGDBBCYII-UHFFFAOYSA-NSMILESCOC1=CC=C(CCCOC(CN2C=CN=C2)C2=CC=C(OC)C=C2)C=C1

Targets

What you can answer from here — as of July 17, 2026

9Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

10+ReferencesStructured and connected to the statements they support

Which drugs share a target with SKF-96365 free base, and which of those have an active Phase 3 trial?

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