Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

BE0022164ProteinHumansPPP2R2D

Substrate-recognition subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. It is acted on by 1 drug in DrugBank.

Gene name
PPP2R2D
UniProtKB entry
Q66LE6Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
453 residues · 52,042 Da
Also known as
KIAA1541 · PP2A subunit B isoform B55-delta · PP2A subunit B isoform delta · PP2A subunit B isoform PR55-delta · PP2A subunit B isoform R2-delta

Resolves to

Protein
UniProtQ66LE6UniProt name2ABD_HUMAN
Gene
HGNCHGNC:23732NCBI Gene55844GeneCardsPPP2R2D
Pharmacology
KEGGhsa:55844
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform, and which indications are they being tested in?

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