Icerguastat

DB16932InvestigationalSmall molecule

Icerguastat: Overview.

Mechanism: Pharmacologically active on Protein phosphatase 1 regulatory subunit 15A and Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Curator reviewed
Formula / weight: C₈H₉ClN₄ · 196.64 g/mol (avg)
Also known as: (2e)-2-((2-chlorophenyl)methylene)hydrazinecarboximidamide · 2-((2-chlorophenyl)methylene)hydrazinecarboximidamide · Sephin 1 · Sephin-1 · Sephin1
Code names: IFB-088 · NSC-65390

Resolves to

Compound

Structure

InChIKeyPDWJALXSRRSUHR-LFYBBSHMSA-NSMILESNC(=N)N\N=C\C1=CC=CC=C1Cl

Targets

What you can answer from here — as of August 30, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

9+ReferencesStructured and connected to the statements they support

Which drugs share a target with Icerguastat, and which of those have an active Phase 3 trial?

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