Inward rectifier potassium channel 2

BE0027705ProteinRatKcnj2

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. It is acted on by 1 drug in DrugBank.

Gene name
Kcnj2
UniProtKB entry
Q64273Swiss-Prot
Cellular location
Cell membrane
Residues / weight
427 residues · 48,200 Da
Also known as
Inward rectifier K(+) channel Kir2.1 · IRK-1 · Irk1 · Potassium channel, inwardly rectifying subfamily J member 2 · RBL-IRK1

Resolves to

Protein
UniProtQ64273UniProt nameKCNJ2_RAT
Gene
NCBI Gene29712
Pharmacology
KEGGrno:29712
Drugs

What you can answer from here — as of December 18, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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32GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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1+ReferenceStructured and connected to the statements they support
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Which compounds in development act on Inward rectifier potassium channel 2, and which indications are they being tested in?

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