NAV

Tetramisole

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Tetramisole is an anthelmintic indicated to treat hookworm infections.

Generic Name
Tetramisole
DrugBank Accession Number
DB16561
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 204.29
Monoisotopic: 204.072119568
Chemical Formula
C11H12N2S
Synonyms
  • Levamisole DL-form
  • Tetramisol
  • Tetramisole
  • Tetramisolum
External IDs
  • 225-729-3
  • NSC-102063
  • R-8299
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Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Treatment ofHookworm infection••••••••••••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

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Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
C8M7RFE4NO
CAS number
5036-02-2
InChI Key
HLFSDGLLUJUHTE-UHFFFAOYSA-N
InChI
InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2
IUPAC Name
6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole
SMILES
C1CN2CC(N=C2S1)C1=CC=CC=C1

References

General References
  1. FDA Thailand: Vermetab (Tetramisole) Oral Tablet [Link]
ChemSpider
3776
ChEBI
77278
ChEMBL
CHEMBL277775
Wikipedia
Levamisole

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet50 mg
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP2.36Chemaxon
pKa (Strongest Basic)6.98Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area15.6 Å2Chemaxon
Rotatable Bond Count1Chemaxon
Refractivity60.08 m3·mol-1Chemaxon
Polarizability22.22 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-7090000000-552fead73534680dc007
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4i-0090000000-7ddaa102dc18fbcb369b
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4i-0190000000-7bfb527434b002c9d9de
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0udi-6490000000-6984601a7861b3366798
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0007-1900000000-3a806c5042fc23f04e52
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0kbf-4900000000-7f756400cbbdcc36f996
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at February 08, 2021 17:04 / Updated at May 05, 2021 20:32