Growth Hormone-Releasing Hormone
- Name
- Growth Hormone-Releasing Hormone
- Accession Number
- DBCAT000076
- Description
A peptide of 44 amino acids in most species that stimulates the release and synthesis of GROWTH HORMONE. GHRF (or GRF) is synthesized by neurons in the ARCUATE NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, GHRF stimulates GH release by the SOMATOTROPHS in the PITUITARY GLAND.
- Drugs
Drug Drug Description Growth hormone-releasing peptide 1 Growth hormone-releasing peptide 1 is under investigation in clinical trial NCT00381602 (A Phase II, Randomized, Cross-over, Vehicle-controlled, Double-blind, Multicenter Study of the Safety, Pharmacodynamics, and Preliminary Efficacy of GHRP-1/AG in... Hexapeptide-2 Not Annotated Pralmorelin Not Annotated Sermorelin For the treatment of dwarfism, prevention of HIV-induced weight loss Tesamorelin A growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy. - Drugs & Drug Targets