Amidohydrolases

Name
Amidohydrolases
Accession Number
DBCAT000093
Description

Biological catalysts and their cofactors.

Drugs
DrugDrug Description
Asparaginase Escherichia coliAn asparaginase enzyme from E. coli used as part of treatment regimens for acute lymphoblastic leukemias.
Asparaginase Erwinia chrysanthemiAn asparagine-specific enzyme used as part of a chemotherapeutic regimen to treat patients with acute lymphoblastic leukemia and lymphoblastic lymphoma.
PegaspargaseA modified form of L-asparagine amidohydrolase used to treat acute lymphoblastic leukemia, which is dependent on an external source of asparagine.
Calaspargase pegolAn asparagine specific enzyme used to treat acute lymphoblastic leukemia.
RibaxamaseRibaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Drugs & Drug Targets
DrugTargetType
Asparaginase Escherichia coliL-asparaginetarget
Asparaginase Escherichia coliThyroxine-binding globulincarrier
PegaspargaseL-asparaginetarget
PegaspargaseThyroxine-binding globulincarrier
Calaspargase pegolL-asparaginetarget