Growth Hormone

Name
Growth Hormone
Accession Number
DBCAT000145
Description

Growth hormone (somatotropin) can be synthesized with methods of recombinant DNA technology. Since action of GH is highly species-specific, recombinant growth hormones of several species (including humans, cows, and pigs) have been developed. They have been used to stimulate growth.

Drugs
DrugDrug Description
SomatotropinA form of recombinant human growth hormone used to treat dwarfism, growth hormone deficiency, and acromegaly as well as to prevent weight loss in HIV patients.
SomatremA recombinant growth hormone used to treat adult growth hormone deficiency and treat disrupted growth in children due to growth hormone insufficiency or deficiency, turner's syndrome, chronic renal failure, and small stature for gestational age.
SomapacitanA human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency.
Somatropin pegolSomatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083).
AlbusomatropinAlbusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency.
Drugs & Drug Targets
DrugTargetType
SomatotropinGrowth hormone receptortarget
SomatotropinProlactin receptortarget
SomatremGrowth hormone receptortarget
SomatremInsulin-like growth factor 1 receptortarget
SomapacitanCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
SomapacitanCytochrome P450 2C12, female-specificenzyme
SomapacitanCytochrome P450 1A2enzyme
SomapacitanCytochrome P450 2C19enzyme
SomapacitanSerum albumincarrier
SomapacitanGrowth hormone receptortarget