Lipids
- Name
- Lipids
- Accession Number
- DBCAT000178
- Description
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
- Drugs
Drug Drug Description Daptomycin A cyclic lipopeptide antibiotic used to treat complicated skin and skin structure infections by susceptible Gram-positive bacteria and bacteremia due to Staphylococcus aureus. Calcitriol An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Ergocalciferol A vitamin found in many supplement products. Cholecalciferol A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. Travoprost A prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension. Mupirocin An antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes. Montelukast A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. Latanoprost An isopropyl ester prodrug used to treat increased intraocular pressure. Mycophenolate mofetil An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants. Bimatoprost A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. Misoprostol A prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers. Fenofibrate A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. Atorvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Vigabatrin An irreversible GABA transaminase inhibitor used as an adjunct therapy to treat refractory complex partial seizures in patients ≥2 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years. Gemfibrozil A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. Alfacalcidol A vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure, as well as some types of rickets and osteomalacia. Fusidic acid A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Tirbanibulin A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp. Desvenlafaxine An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. Unoprostone A prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents. Tafluprost An ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Omega-3-acid ethyl esters A mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia. Rice bran oil Rice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It... Selexipag A non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension. Triheptanoin Triheptanoin is a medium chain triglyceride indicated to provide calories and fatty acids to treat long chain fatty acid oxidation disorders. Clascoterone An androgen receptor antagonist used for the topical treatment of acne vulgaris in patients 12 years of age and older. Somapacitan A human growth hormone analog subcutaneous injection indicated for adults with growth hormone deficiency. Oritavancin An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria. Docosanol An antiviral used to treat orofacial herpes sores. Alprostadil A medication used to treat erectile dysfunction. Butyl alcohol Not Available Isoamyl alcohol Not Available 2-Butanol Not Available Fumagillin Not Available Bombykol Not Available Tricosanoic acid Not Available Heptane-1,2,3-Triol Not Available Palmitoleic Acid Not Available Lucinactant Intended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS. C31G Investigated for use/treatment in contraception, HIV infection, and prevention of stdis. Elacytarabine Investigated for use/treatment in leukemia (unspecified) and melanoma. Cobiprostone Investigated for use/treatment in cystic fibrosis. Iodofiltic acid I-123 Investigated for use/treatment in cardiac ischemia. 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid Metabolic product of biphenyl; from Pseudomonas putida. 11-MERCAPTOUNDECANOIC ACID Not Available Gemeprost A prostaglandin E1 analogue used for cervical dilation and, in combination with mifepristone, for pregnancy termination. Limaprost An oral prostaglandin E1 analogue used to improve symptoms associated with thromboangiitis obliterans, acquired lumbar spinal canal stenosis, and other ischemic conditions. Cetyl alcohol No therapeutic indications in medicinal products. Indicated to be used as an indirect additive in food contact substances, or an ingredient in commercial or cosmetic products. Octacosanol 1-octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. This high–molecular-weight organic compound is the main component of a natural product wax extracted... Cetalkonium An antiseptic used as a preservative or to treat certain topical infections. VTP-194204 Nrx194204 has been used in trials studying the treatment of Parkinson's Disease and Non-small Cell Lung Cancer. Mapracorat Mapracorat has been investigated for the treatment of Eczema and Atopic Dermatitis. 9CUAB30 9 Cuab30 has been used in trials studying the treatment and prevention of HER2/Neu Positive, HER2/Neu Negative, No Evidence of Disease, Estrogen Receptor Negative, and estrogen receptor positive, among others. Lifibrol Lifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia. Tiadenol Not Annotated Methylpentynol Not Annotated Gondoic acid Not Annotated Osbond acid Not Annotated Octyldodecanol Not Annotated Royal jelly Royal jelly is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug. Caprylyl glycol Not Annotated Amyl acetate Not Annotated Stearyl alcohol Not Annotated Selgantolimod Selgantolimod is under investigation in clinical trial NCT03491553 (Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-suppressed Adults With Chronic Hepatitis B). Spermaceti A lubricant used in medications to treat constipation associated with hemorrhoids. alpha-Linolenic acid A polyunsaturated omega-3 fatty acid found in many supplements. Phosphatidyl serine A nutrient used in some supplement products. Calcifediol An active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients. Dihomo-gamma-linolenic acid For nutritional supplementation, also for treating dietary shortage or imbalance Icosapent A polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements. Lipoic acid For nutritional supplementation, also for treating dietary shortage or imbalance. Calcium acetate A phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism. Valproic acid An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. Treprostinil A prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol. Carboprost tromethamine A prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective. Sodium tetradecyl sulfate An anionic surfactant used to treat varicose veins of the lower extremities. Caspofungin An echinocandin used to treat a variety of fungal infections. Candoxatril Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor. Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Sodium lauryl sulfate An anionic surfactant used in cosmetics and pharmaceuticals as a fat emulsifier, wetting agent, and detergent. Paricalcitol A vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease. Dinoprostone A prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. Ethiodized oil A contrast agent used in imaging procedures. Lubiprostone A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. Dihydrotachysterol A synthetic analog of vitamin D that does not require renal activation like vitamin D2 or Vitamin D3. Iloprost A synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH). Fluvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Colistimethate An antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa. Micafungin An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation. Dinoprost tromethamine Used for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities... Ridogrel Used as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction. Epoprostenol A vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure. Aluminium monostearate Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging... gamma-Hydroxybutyric acid Used as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance. Tiaprofenic acid A nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis. Propyl acetate Not Available 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine Not Available Glycerol 2-phosphate Not Available Cholesterol sulfate Component of human seminal plasma & spermatozoa. TU-514 Not Available Hexadecanesulfonyl fluoride Not Available Prostaglandin D2 The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important... Cholesteryl Linoleate Not Available 4-Oxosebacic Acid Not Available Platelet Activating Factor Not Available Calcipotriol A topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis. Prostaglandin B2 Not Available 12-Bromododecanoic Acid Not Available 4-(2-Thienyl)Butyric Acid Not Available Methoxy arachidonyl fluorophosphonate Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid... Farnesol A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in... Isobutyric acid Not Available Indolepropionic acid Not Available Ricinoleic acid Not Available Lauric acid Lauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. Lauric acid is a solid at room temperature but melts easily... Acetic acid An antimicrobial agent used to treat susceptible infections of the external auditory canal. Stearic acid An ingredient found in topical products as a skin protectant. Lysophosphatidylglycerol Not Available N-hexadecanoylglycine Not Available Lexacalcitol Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane. It is known... sn-glycero-3-phosphoethanolamine Not Available Butyric Acid A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester. Capric acid Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include... Lanosterol Not Available Cyclohexanol Monohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers. [PubChem] 12-Hydroxydodecanoic Acid Not Available 2-Methylbutanoic Acid Not Available Isovaleric Acid Not Available Doconexent An omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. Dihydrolipoic Acid Not Available Propanoic acid An antimicrobial food additive. Palmitic Acid A fatty used as a food additive and emollient or surfactant in cosmetics. Eucalyptol A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. Cadaverine Cadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine. Prostaglandin G2 A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem] tert-butanol Not Available Dodecyl sulfate Not Available Isocaproic acid Not Available 5-phenylpentanoic acid Not Available Indole-3-Glycerol Phosphate Not Available Valpromide A valproic acid derivative used to treat epilepsy and as adjunct therapy for psychomotor agitation, depression, and manic episodes of bipolar disorder. Mdl-29951 Not Available Oleic Acid A naturally occurring fatty acid with antibacterial properties added to a variety of drug products. Seocalcitol Not Available KH064 Not Available Phosphatidylethanolamine Not Available L-Dilinoleoyllecithin Not Available Caprylic acid Caprylic acid is an eight-carbon chain fatty acid, also known systematically as octanoic acid. It is found naturally in coconuts and breast milk. It is an oily liquid with a... Cholesterol The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Arachidonic Acid A natural fatty acid that plays an essential role in physiological homeostases, such as repair and growth of cells. 4,7-Dioxosebacic Acid Not Available Choline alfoscerate A natural choline that is used to manage declining cognitive function associated with neurodegenerative and vascular diseases. 20-hydroxycholesterol Not Available 25-Hydroxycholesterol Not Available 7beta-hydroxycholesterol Not Available Sulfatide Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy. 5-hydroxyvaleric acid Not Available Inecalcitol Investigated for use/treatment in prostate cancer, psoriasis and hyperparathyroidism. cis-Vaccenic acid Not Available Benoxaprofen The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets... Dexloxiglumide For the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD). Oleoyl-estrone For the treatment of obesity. Voglibose An alpha-glucosidase inhibitor indicated in the management of postprandial blood glucose in patients with type II diabetes. Becocalcidiol For topical treatment of psoriasis and psoriatic disorders. Eritoran Investigated for use/treatment in sepsis and septicemia. Pumactant Investigated for use/treatment in asthma, lung injury, and surgical adhesions. AN-9 Investigated for use/treatment in liver cancer, lung cancer, melanoma, and leukemia (lymphoid). Gemcabene Investigated for use/treatment in atherosclerosis, cardiovascular disorders, and hyperlipidemia. Aminocandin Investigated for use/treatment in fungal infections. Elafibranor Investigated for use/treatment in atherosclerosis and diabetes mellitus type 2. AM103 For the treatment of asthma and cardiovascular disease. Beraprost For the treatment of pulmonary hypertension. Fenoxaprop-ethyl Chronic angina and Coronary Artery Disease Caprospinol Alzheimer's Disease Arundic acid Investigated for use/treatment in cerebral ischemia. Emricasan Investigated for use/treatment in hepatitis (viral, C), liver disease, and transplantation (organ or tissue). ETC-588 Investigated for use/treatment in atherosclerosis, coronary artery disease, and vascular diseases. AZD-9684 Investigated for use/treatment in thrombosis. Varespladib methyl Investigated for use/treatment in atherosclerosis and coronary artery disease. DP-VPA Investigated for use/treatment in bipolar disorders, epilepsy, and migraine and cluster headaches. AGI-1096 Investigated for use/treatment in transplant (rejection). 1alpha,24S-Dihydroxyvitamin D2 Investigated for use/treatment in parathyroid disorders. Elocalcitol Investigated for use/treatment in benign prostatic hyperplasia, urinary incontinence, prostate disorders, and infertility. Maxacalcitol Not Annotated Fiboflapon Investigated for use/treatment in inflammatory disorders (unspecified). Doxercalciferol A synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis. Calfactant A lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants. E5531 Investigated for use/treatment in sepsis and septicemia. Priralfinamide Investigated for use/treatment in pain (acute or chronic). Ethanolamine oleate A mild sclerosing agent used in the treatment of esophageal varices with recent bleeding episodes. Zaltoprofen A non-steroidal anti-inflammatory drug approved for use in Japan in 1993. Seratrodast Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. Capsaicin A topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. Monoctanoin Monoctanoin is used to dissolve cholesterol gallstones. 1-Dodecanol 1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals. (From McGraw-Hill Dictionary... GW-590735 Not Available Sobetirome Not Available Sebacic acid Not Available ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID Not Available IDD594 Not Available Myristic acid Not Available Efaproxiral Not Available Leukotriene C4 The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates... Teriflunomide A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. Icosapent ethyl An ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia. Beclamide Has been used in the management of epilepsy and epilepsy related behavioural disorders. It was used for generalised tonic-clonic seizures, and was not effective for absence seizures. More recently focus... Poractant alfa A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Colfosceril palmitate A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Zucapsaicin A topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients. Uridine triacetate A pyrimidine analog used for the reversal of overdose, regardless of the presence of symptoms, and early-onset, severe or life-threatening CNS toxicity or cardiotoxicity of fluorouracil or capecitabine. Pivhydrazine For the treatment of depression. Soybean oil An oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency. Safflower oil No approved therapeutic indications. Methyl salicylate A topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons. Sodium glycerophosphate A medication used to treat hypophosphatemia. Olive oil For use in adults as a source of calories and fatty acids in total parenteral nutrition [FDA Label]. Sometimes used as an additive in cosmetic products. Cedar oil An extract from Juniperus virginiana used in allergy testing. Cocoa butter Indicated for topical use in over-the-counter skin products for the treatment of skin dryness and reduction of striae gravidarum (stretch marks). Lanolin An ingredient used in skin care products to relieve irritation. Castor oil An ingredient used in a variety of natural health products. Eucalyptus oil An ingredient used in a variety of natural health products. Undecylenic acid An antifungal used to treat tinea species infections. Turpentine A medication used to treat minor aches and pains of muscles and joints. Omega-3 fatty acids An ingredient found in a variety of supplements and vitamins. Calcium threonate No approved therapeutic indications. Sesame oil Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic... L-threonic acid Not Annotated Peppermint oil An ingredient used in a variety of natural health products and is not an approved medication. Tea tree oil Indicated for topical use to help protect against infection in minor cuts, scrapes, and burns. No FDA-approved therapeutic indications. Borage oil Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as... Glyceryl monostearate Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods. Calcium glycerophosphate An medication used to treat low levels of phosphate or calcium, as well as an ingredient in dental products to prevent dental caries. DL-dimyristoylphosphatidylcholine DL-dimyristoylphosphatidylcholine is not an active pharmaceutical agent and has no indication. DL-dimyristoylphosphatidylglycerol DL-dimyristoylphosphatidylglycerol is not an considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indications. Cod liver oil An ingredient found in a variety of nutritional products. Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Soy sterol Not Annotated Linseed oil Linseed oil is a rich source of α-Linolenic acid extracted from the dried, ripened seeds of the flax plant Linum usitatissimum. Other fatty acids contained in linseed oil include palmitic... Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Chlorobutanol No approved therapeutic indications on its own. Fenprostalene Not Annotated Luprostiol Not Annotated Monensin Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds. Prostalene Analog of prostaglandin F2 alpha. Amphomycin Not Annotated Cloprostenol Not Annotated Fluprostenol Not Annotated Beeswax Beeswax is also characterized by several therapeutic properties of great interest to us; it is thought to be particularly effective in healing bruises, inflammation and burns. Recently, the interest of... Latanoprostene bunod A prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma. Tanzisertib Tanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others. Leukotriene D4 Leukotriene D4 has been used in trials studying the diagnostic of Asthma and Allergic Rhinitis. Verinurad Verinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia. Varespladib Varespladib has been investigated for the treatment and prevention of Sickle Cell Disease, Vaso-occlusive Crisis, and Acute Coronary Syndrome. Ingavirin Ingavirin has been used in trials studying the treatment of Influenza and Common Cold. Lomibuvir Lomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection. Atagabalin Atagabalin has been used in trials studying the treatment of Insomnia, Primary Insomnia, and Nonrestorative Sleep. Letermovir An antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT). Orantinib Orantinib has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Kidney Cancer, Gastric Cancer, and Prostate Cancer, among others. Surotomycin Surotomycin has been used in trials studying the treatment of Diarrhea and Clostridium Difficile Infection. It is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents for... Gefarnate Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease. Ritobegron Ritobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin... Devimistat Devimistat (CPI-613) has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Advanced Cancer, and Pancreatic Cancer, among others. Tricaprylin Tricaprilin has been used in trials studying the supportive care and treatment of Alzheimer's Disease. KRN-7000 KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients... Siagoside Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a... Seladelpar Seladelpar (MBX-8025) has been used in trials studying the treatment of Hyperlipidemia. Caprylic alcohol Caprylic alcohol has been used in trials studying the treatment of Essential Tremor. Ralinepag Ralinepag has been used in trials studying the treatment of Pulmonary Arterial Hypertension. Imiglitazar Imiglitazar has been used in trials studying the treatment of Diabetes Mellitus. Taprenepag Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle. 3,5-diiodothyropropionic acid DITPA has been investigated in Congestive Heart Failure. Salirasib Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung. Sulprostone A prostaglandin analogue used to treat post-partum hemorrhaging, induce medical abortion, and induce labour in instances of in utero fetal death. Tributyrin Tributyrin has been used in trials studying the treatment of Prostate Cancer and Unspecified Adult Solid Tumor, Protocol Specific. Bindarit Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy. Rivipansel Rivipansel has been used in trials studying the other, basic science, and treatment of Pain Crisis, Renal impairment, Anemia, Sickle Cell, Sickle Cell Disease, and Sickle Cell Disorders, among others. Dinoprost A medication used to induce a second trimester abortion. CMX-2043 CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. MK-0752 Mk 0752 is under investigation in clinical trial NCT00572182 (MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer). Pradigastat Pradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD). Leukotriene B4 Leukotriene B4 has been used in trials studying the treatment of HIV Infections. LY-518674 LY518674 has been used in trials studying the treatment of Metabolic Syndrome X. Icosabutate Icosabutate is under investigation in clinical trial NCT02373176 ([14C] Icosabutate -A Phase I Absorption, Metabolism and Excretion Study). AQX-1125 AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome. MK-8245 MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus. Glyceryl Trioleate Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy. 1alpha-Hydroxyvitamin D5 1alpha-Hydroxyvitamin D5 (CARD-024) has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity. Resolvin E1 Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers). Glycovir Glycovir has been used in trials studying the treatment of HIV Infections. Levomenol Levomenol has been known to elicit a number of potentially beneficial pharmacological effects, including anti-irritant, anti-inflammatory, and anti-microbial actions. Bisabolol is also demonstrated to enhance the percutaneous absorption of certain... Terpin hydrate An expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract. Omega-6 fatty acids There are no current pharmacotherapeutic products based on omega-6 fatty acids. Glyceryl 1-oleate Not Available Fentiazac Not Annotated Alminoprofen Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances. Iodine (131I) norcholesterol A radioiodine-labeled cholesterol analogue that accumulates in areas where steroid hormones are produced and is used in certain diagnostic procedures. Cyclobutyrol Not Annotated Pranoprofen A topical anti-inflammatory agent used for the treatment of non-infectious inflammatory conditions such as blepharitis and conjunctivitis. Pranoprofen ophthalmic solution may also be used post-operatively to manage inflammation. Mifamurtide A muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection. Tacalcitol A vitamin D analog indicated in the treatment of mild to moderate plaque psoriasis. Enprostil Not Annotated Gamolenic acid An ingredient found in a variety of nutritional products. Fish oil A source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement. Peanut oil A compound used to lubricate ear wax, as an emollient, and used in laxatives. Isopropyl myristate A polar skin moisturizer that is used to enhance skin penetration of drugs. Magnesium acetate Not Available beta-Sitosterol Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity. Palmidrol A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food... Malacidin A Malacidin A is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . Malacidin B Malacidin B is being investigated for its antibiotic action and has potential for use as an antibacterial agent in the future . Magnesium stearate Not Annotated Morrhuic acid Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil. 1,2-Distearoyllecithin Not Annotated Triethylhexanoin Triethylhexanoin is an ingredient of cosmetic products as a fragrant solvent. Linoleic acid Not Annotated Ceramide NP Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. Ceramide 3... Menthol Not Annotated Threonic acid Not Annotated Jojoba oil Jojoba oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Wormwood Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Meadowfoam seed oil Meadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Argan oil Argan oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Coconut oil Coconut oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Bergamot oil Bergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Palm oil Palm oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug. Acetate Not Annotated Aluminum acetate A medication used for temporary relief of skin irritation. Lavender oil Not Annotated Acetyl chloride Not Annotated Rosemary oil Not Annotated Ceramide AP Not Annotated Ceramide NG Not Annotated Etrasimod Etrasimod is under investigation in clinical trial NCT03945188 (Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis). Uproleselan Uproleselan is under investigation in clinical trial NCT02306291 (Study to Determine Safety, Pharmacokinetics and Efficacy of GMI-1271 in Combination With Chemotherapy in AML). AZD-7687 AZD-7687 is under investigation in clinical trial NCT01119352 (AZD7687 Multiple Ascending Dose Study). Edasalonexent Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes). CXA-10 CXA-10 is under investigation in clinical trial NCT03422510 (FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS)). Pemafibrate Pemafibrate is under investigation in clinical trial NCT03350165 (A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)). Bulevirtide A drug for the treatment of chronic Hepatitis D infection in adults with compensated liver disease. VB-201 VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis). Navtemadlin Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia). beta-Hydroxyisovaleric acid beta-Hydroxyisovaleric acid is under investigation in clinical trial NCT03018496 (Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.). Dihydrocapsiate Dihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate). GLPG-0974 GLPG-0974 is under investigation in clinical trial NCT01721980 (Multiple Ascending Dose Study of GLPG0974 in Healthy Subjects). Setogepram Setogepram is under investigation in clinical trial NCT03184584 (Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome). 24-Homo-1,25-dihydroxyvitamin D3 24-Homo-1,25-dihydroxyvitamin D3 is a novel vitamin D analogue. Previtamin D(3) Not Annotated Islatravir Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)). Anise oil Not Annotated Cetyl palmitate Not Annotated Lecithin Fatty substances commonly found in nutritional supplements. Menthone A medication used to treat stone formation in the gallbladder and liver. Cajuput oil An ingredient used in topical products for mild analgesia. Thioctamide An ingredient in nutritional products for liver health. Naxitamab A GD2-targeted IgG1 monoclonal antibody for the treatment of high-risk relapsed/refractory neuroblastoma of the bone or bone marrow. Triacetin An acetylating agent indicated in the treatment of ringworm. alpha-Hydroxylinoleic acid alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study). AK106-001616 AK106-001616 is under investigation in clinical trial NCT01285752 (A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA)). Adelmidrol Adelmidrol is under investigation in clinical trial NCT01420510 (Saginil in vs. Placebo for Gynecologic Oncology Patients Affected by Vaginitis). Axomadol Axomadol is under investigation in clinical trial NCT01043263 (Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain). Ecraprost Ecraprost is under investigation in clinical trial NCT00059657 (Efficacy/safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease). Firsocostat Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)). Nangibotide Nangibotide is under investigation in clinical trial NCT04055909 (Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock). Odevixibat An ileal sodium/bile acid cotransporter inhibitor indicated in the treatment of pruritus in patients with progressive familial intrahepatic cholestasis. Rivenprost Rivenprost is under investigation in clinical trial NCT00296556 (Therapeutic Study of ONO-4819CD for Ulcerative Colitis). ABX-196 ABX-196 is under investigation in clinical trial NCT03897543 (ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma). Oleic monoethanolamide Not Available Wheat germ oil Not Annotated Citronella oil Not Annotated Thyme oil Not Annotated Glyceryl laurate Not Annotated Medium-chain triglycerides A source of essential fatty acids used as a source of calories in parenteral nutrition. Undecanoic acid Not Annotated Arachidonyltrifluoromethane Specific inhibitor of phospholipase A2. Iopofosine I-131 Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned). - Drugs & Drug Targets