7beta-hydroxycholesterol

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DB04706ExperimentalSmall molecule

7beta-hydroxycholesterol: Overview.

Mechanism: Pharmacologically active on Protein kinase C alpha type and Disintegrin and metalloproteinase domain-containing protein 17
Curator reviewed
Formula / weight: C₂₇H₄₆O₂ · 402.6529 g/mol (avg)
Also known as: (3β,7β)-cholest-5-ene-3,7-diol · 7β-hydroxycholesterol

Resolves to

Compound

UNIIN9616291J4CAS566-27-8ChEMBLCHEMBL497834ChEBI42989PubChem473141

Structure

InChIKeyOYXZMSRRJOYLLO-KGZHIOMZSA-NSMILES[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C

Targets

P17252PRKCAP78536ADAM17

What you can answer from here — as of September 12, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with 7beta-hydroxycholesterol, and which of those have an active Phase 3 trial?

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