Amines
- Name
- Amines
- Accession Number
- DBCAT000266
- Description
A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)
- Drugs
Drug Drug Description 1-Phenylcyclohexylamine Not Available 2-(aminomethyl)phenol 2-(aminomethyl)phenol is under investigation in clinical trial NCT03556319 (2-HOBA: Multiple Dosing Study in Older Adults). 2-Aminophenol Not Available 2-Fluoroaniline Not Available 2,5-Dimethoxy-4-ethylamphetamine Not Available 2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine (ALEPH-2) is a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties. 2,5-Dimethoxyamphetamine Not Available 3-(cyclohexylamino)propanesulfonic acid Not Available 3-Phenylpropylamine Not Available 3,4-dimethylaniline Not Available 3,5-Difluoroaniline Not Available 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Not Available 4-(Isopropylamino)diphenylamine 4-(Isopropylamino)diphenylamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... 4-Bromo-2,5-dimethoxyphenethylamine Not Available 4-dimethylaminophenol Not Annotated 4-Methoxyamphetamine Not Available 4-Phenylbutylamine Not Available 4-Phospho-D-erythronohydroxamic acid Not Available 4,5-Dimethyl-1,2-phenylenediamine Not Available 5-Methoxy-N,N-diisopropyltryptamine 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a... 5-methoxy-N,N-dimethyltryptamine 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug,... 6-bromoindirubin-3'-oxime Not Available 6-hydroxydopa quinone Not Available 8-anilinonaphthalene-1-sulfonic acid Not Available Abemaciclib A medication used to treat HR+ HER2- advanced or metastatic breast cancer. Abexinostat Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase... ABT-751 ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer. Acebutolol A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults. Acetaminophen An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. Acetohydroxamic acid A synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract. Acetyl sulfisoxazole Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the... Acetylcarnitine An acetylated form of the amino acid derivative L-carnitine that assists in mitochondrial fatty acid metabolism. It is under investigation as a treatment for numerous conditions, including neuropathy, depression, and dementia. Acetylcholine A parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. Acetyldinaline Acetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma). Acoltremon Acoltremon is under investigation in clinical trial NCT05493111 (A Long-term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512). Adrafinil Used to relieve excessive sleepiness and inattention in elderly patients. Adrenalone Not Annotated Afuresertib Afuresertib has been used in trials studying the treatment of Cancer and Neoplasms, Haematologic. Albuterol A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms. Alcuronium A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant. Alethine Investigated for use/treatment in blood (blood forming organ disorders, unspecified), lymphoma (unspecified), and multiple myeloma. Alifedrine Alifedrine is a small molecule drug. The usage of the INN stem '-drine' in the name indicates that Alifedrine is a sympathomimetic. Alifedrine has a monoisotopic molecular weight of 289.2... Alilusem Alilusem is a small molecule drug. Alilusem has a monoisotopic molecular weight of 394.04 Da. Almotriptan A 5-HT1B/1D receptor agonist used to treat migraines. Alniditan Alniditan is a small molecule drug. Alniditan has a monoisotopic molecular weight of 302.21 Da. Alprazolam A triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. Alprenolol For the treatment of hypertension, angina, and arrhythmia Altiratinib Not Annotated Alverine A smooth muscle relaxant used to relieve abdominal pain associated with gastrointestinal conditions like heartburn, flatulence, and Irritable Bowel Syndrome. Ambenonium A cholinesterase inhibitor that targets both muscarinic and nicotinic receptors indicated for the treatment of myasthenia gravis. Ambroxol A medication indicated for airway secretion clearance therapy. Ambroxol acefyllinate A bronchodilator indicated in the symptomatic treatment of bronchopulmonary disorders associated with bronchospasm. Amidephrine A sympathomimetic indicated in the treatment of acute, chronic, vasomotor, and allergic rhinitis. Amifampridine A voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome. Amiflamine Amiflamine is a small molecule drug. Amiflamine has a monoisotopic molecular weight of 192.16 Da. Aminooxyacetic acid A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem] Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Amiselimod Not Available Amitraz Amitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as... Amlexanox Used as a paste in the mouth to treat aphthous ulcers (canker sores). Amoscanate Amoscanate is a small molecule drug. Amoscanate has a monoisotopic molecular weight of 271.04 Da. Amphetamine A CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Amrinone A positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure. Ancriviroc Ancriviroc is a small molecule drug. The usage of the INN stem '-viroc' in the name indicates that Ancriviroc is a CCR5 (Chemokine CC motif receptor 5) receptor antagonist. Ancriviroc... Andarine Andarine is a non-steroidal selective androgen receptor modulator. Aniline Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. Being a precursor... Arbutamine Used to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in... Arformoterol A beta-2 adrenergic agonist and bronchodilator used for long-term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Arimoclomol A heat-shock protein co-inducer used to treat neurological symptoms of Niemann-Pick disease type C in combination with miglustat. Arotinolol Artinolol was introduced to be used as an antihypertensive agent since 1986. It has been studied for other functions like tremor control for patients with Parkinson disease and it is... Asoprisnil Investigated for use/treatment in uterine fibroids. AT-13148 Not Annotated Atenolol A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients. Atomoxetine A selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD). Avacopan An orally bioavailable complement 5a receptor (C5aR) antagonist for the treatment of severe anti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis. Avitriptan Avitriptan is a small molecule drug. The usage of the INN stem '-triptan' in the name indicates that Avitriptan is a sumatriptan derivative serotonin (5HT1) receptor agonist. Avitriptan has a... Azalanstat Azalanstat is a small molecule drug. Azalanstat has a monoisotopic molecular weight of 429.13 Da. AZD 3355 Investigated for use/treatment in gastroesophageal reflux disease (GERD). AZD-8186 AZD-8186 is under investigation in clinical trial NCT03218826 (PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be... Azosemide Azosemide is a loop diuretic used to treat hypertension, edema, and ascites. Bambuterol A long acting beta2-adrenoceptor agonist for the management of lung diseases associated with bronchospasm. Bamethan Not Annotated Barzuxetan Barzuxetan is a small molecule drug. The usage of the INN stem '-xetan' in the name indicates that Barzuxetan is a chelating agent. Barzuxetan has a monoisotopic molecular weight of... Bb-3497 Not Available Befunolol Used in the management of open angle glaucoma. PMID: 12480285. Belinostat A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). Beloxamide Beloxamide is a small molecule drug. Beloxamide has a monoisotopic molecular weight of 283.16 Da. Benfluorex Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended... Benorilate Not Annotated Benurestat Benurestat is a small molecule drug. The usage of the INN stem '-restat' in the name indicates that Benurestat is a aldose reductase inhibitor. Benurestat has a monoisotopic molecular weight... Benzalkonium An antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products. Benzethonium A medication used as to clean hands and clean minor cuts and scrapes. Benzhydroxamic Acid Not Available Benzododecinium Benzododecinium is used as an antiseptic/disinfectant compound. It has been marketed as a tincture for antiseptic product for wounds in the Czech Republic. Benzonatate A non-narcotic oral antitussive drug used to suppress coughing. Benzoxonium An antiseptic indicated in skin disinfection and prevention of infections. Benzphetamine A sympathomimetic used to manage exogenous obesity short term. Benzylamine Not Available Betaine A methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels. Betaine aldehyde Not Available Betaxolol A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically). Bethanechol A muscarinic agonist used to treat postoperative and postpartum nonobstructive functional urinary retention and neurogenic atony of the bladder with retention. Bevantolol For the treatment of angina pectoris and hypertension. Bicalutamide An androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate. Birabresib Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)). Bisoprolol A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension. Bitolterol Used to dilate air passages in the lungs that have become narrowed as a result of disease or inflammation. It is used in the treatment of asthma and chronic obstructive... Bixalomer Bixalomer is under investigation in clinical trial NCT01115985 (A Study to Assess the Effect of ASP1585 on Pharmacokinetics of Atorvastatin in Healthy Volunteers). BMS-777607 BMS-777607 has been investigated for the basic science of Malignant Solid Tumour. Bopindolol For the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Bosutinib An antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments. Brasofensine For the treatment of Parkinson's Disease. Bretylium A norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias. Brilliant blue G A disclosing agent used in ophthalmological surgery to stain the internal limiting membrane (ILM). Brilliant green cation An ingredient used in topical medications to prevent infections of the umbilical cord. Brolamfetamine Not Available Bromhexine A mucolytic drug used to decrease the viscosity of mucus in the airway, enhancing mucus clearance. Bromodiphenhydramine For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive. Bromotheophylline Bromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with... Bucetin Bucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication. Bucindolol Bucindolol has been investigated in Heart Failure. Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Bufuralol Bufuralol is a new, non-selective -adrenoceptor blocking agent. Buparlisib Buparlisib has been used in trials studying the treatment and basic science of Lymphoma, Metastases, Lung Cancer, Solid Tumors, and Breast Cancer, among others. Bupivacaine A local anesthetic used in a wide variety of superficial and invasive procedures. Bupranolol Used to manage hypertension and tachycardia. Also used to treat glaucoma. Butafosfan Butafosfan is a small molecule drug. Butafosfan has a monoisotopic molecular weight of 179.11 Da. Butanilicaine Not Annotated Butenafine A topical antifungal used to treat tinea versicolor, tinea pedis, tinea cruris, and tinea corporis. Butylamine Butylamine is a colourless liquid which acquires a yellow colour upon storage in air. It is one of the four isomeric amines of butane. It is known to have the... Butylscopolamine An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain. Butyrylthiocholine A sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity. [PubChem] C31G Investigated for use/treatment in contraception, HIV infection, and prevention of stdis. Cabozantinib A tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer. Cadaverine Cadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine. Cafedrine Cafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Calcium pangamate Not Annotated Calmangafodipir Not Annotated Capadenoson Capadenoson is under investigation in clinical trial NCT00518921 (Capadenoson in Angina Pectoris). Caprylhydroxamic acid Not Annotated Carbamoylcholine A direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. Carbidopa A dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms. Carboxin A systemic agricultural fungicide and seed treatment agent. Carbuterol Not Annotated Carmoterol A long acting beta-2 agonist indicated in the treatment of COPD, asthma, and chronic bronchitis. Carteolol A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma. Carvedilol A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. Cathine Used to decrease appetite. CC-90001 Not Annotated Celiprolol A beta-blocker for the management of hypertension and angina pectoris. Cemdomespib Cemdomespib is under investigation in clinical trial NCT05895552 (A Phase 2 Study of RTA 901 in Patients With Diabetic Peripheral Neuropathic Pain (CYPRESS)). Cetalkonium An antiseptic used as a preservative or to treat certain topical infections. Cetrimonium A compound that can be used as a topical antiseptic. Cetyltrimethylammonium naproxenate An anti-inflammatory and antiseptic agent indicated to treat mouth inflammation and pain , including that caused by tooth extraction. CGC-11047 Investigated for use/treatment in lymphoma (unspecified), macular degeneration, prostate cancer, and solid tumors. CGS-27023 Not Available Chlorisondamine Not Annotated Chloropyramine For the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Chlorothen Chlorothen is a small molecule drug. Chlorothen has a monoisotopic molecular weight of 295.09 Da. Chlorphenoxamine An antihistamine used as an antipruritic. Chlorphentermine Used as an appetite suppressant. Chlorsulfaquinoxaline Chlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer. Choline A nutrient found in a wide variety of vitamins including pre-natal formulations. Choline magnesium trisalicylate Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. Choline salicylate The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due... Ciramadol Ciramadol is a small molecule drug. The usage of the INN stem '-adol/-adol-' in the name indicates that Ciramadol is a analgesic. Ciramadol has a monoisotopic molecular weight of 249.17... Citalopram A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression. Citicoline An endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects. Clenbuterol A decongestant and bronchodilator used in a variety of respiratory conditions. Clioxanide Clioxanide is a small molecule drug. Clioxanide has a monoisotopic molecular weight of 540.84 Da. Clobenzorex Not Annotated Clobutinol Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in... Clofedanol An antitussive used for the symptomatic relief of acute cough caused by minor throat and bronchial irritation. Cloflucarban Cloflucarban is a small molecule drug. Cloflucarban has a monoisotopic molecular weight of 348.0 Da. Cloforex Cloforex is a small molecule drug. Cloforex has a monoisotopic molecular weight of 255.1 Da. Cloranolol Not Annotated Clorgiline An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE. Clorsulon Not Annotated Clovoxamine Clovoxamine is a small molecule drug. Clovoxamine has a monoisotopic molecular weight of 284.13 Da. Cocamidopropyl betaine Cocamidopropyl betaine is a mixture of closely related organic compounds derived from coconut oil and dimethylaminopropylamine that typically acts as an amphoteric surfactant in cosmetics and personal care products. It... Coco diethanolamide Not Annotated Colesevelam A bile acid sequestrant used to lower LDL-C in adults with hyperlipidemia and pediatric patients with heterozygous familial hypercholesterolemia, and to improve glycemic control in type 2 diabetes. Colestipol A bile acid sequestrant used as an adjunct to diet and exercise to reduce LDL-C cholesterol levels in patients with primary hypercholesterolemia. Coprogen Not Available Crotamiton A topical scabicidal and antipruritic agent used for scabies eradication and for the relief of pruritus. CTS-1027 CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection. CUDC-101 CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others. Cumidine Not Available Cysteamine A cystine depleting agent used to treat the effects of cystinosis. Dabrafenib A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. Dacinostat Dacinostat is a novel histone deacetylase inhibitor. Dalfampridine A potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS). Danicopan A small molecule complement factor D inhibitor used to treat extravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria. Dapoxetine A selective serotonin reuptake inhibitor used in the treatment of premature ejaculation. Darapladib Investigated for use/treatment in atherosclerosis. Dasabuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Dasotraline Dasotraline is a serotonin, norepinephrine and dopamine reuptake inhibitor (SNDRI) that is under investigation for the treatment of Binge Eating Disorder, Adult Attention Hyperactivity Disorder, Attention Deficit Hyperactivity Disorder, and... Deanol Deanol is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA). It holds tertiary amine and primary alcohol groups as functional groups. Deanol has been used in the treatment... Decamethonium For use as a skeletal muscle relaxant Decamethoxine Not Annotated Deferoxamine A chelating agent used to treat iron or aluminum toxicity and some blood transfusion dependent anemias. Demecarium For the topical treatment of chronic open-angle glaucoma. Demelverine Demelverine is a small molecule drug. The usage of the INN stem '-verine' in the name indicates that Demelverine is a spasmolytic with a papaverine-like action. Demelverine has a monoisotopic... Denatonium Not Available Denopamine Denopamine is a small molecule drug. Denopamine has a monoisotopic molecular weight of 317.16 Da. Deoxyepinephrine Sympathomimetic, vasoconstrictor agent. Derazantinib Derazantinib is under investigation in clinical trial NCT03230318 (Derazantinib in Subjects With FGFR2 Gene Fusion Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma). Desmethylsertraline Desmethylsertraline is a metabolite of sertraline. Dexfenfluramine For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet Dexpropranolol Not Available Dextroamphetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. Dexverapamil Not Annotated Diacetamate Diacetamate is a small molecule drug. Diacetamate has a monoisotopic molecular weight of 193.07 Da. Diamfenetide Diamfenetide is a small molecule drug. Diamfenetide has a monoisotopic molecular weight of 372.17 Da. Diazoxide A non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions. Dibromsalan Dibromsalan is a small molecule drug. Dibromsalan has a monoisotopic molecular weight of 368.9 Da. Dichloroisoproterenol Dichloroisoproterenol has been used in trials studying the treatment and basic science of Insulin Resistance and Polycystic Ovary Syndrome. Diclofenac An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Diclofurime Diclofurime is a small molecule drug. Diclofurime has a monoisotopic molecular weight of 384.1 Da. Didecyldimethylammonium A disinfectant and microbicidal agent used in a variety of products. Didox Didox has been used in trials studying the supportive care of Gastric Cancer. Diethanolamine Diethanolamine is a small molecule drug. Diethanolamine is under investigation in clinical trial NCT02499549 (Two Treatment Regimens of Cocamide DEA Lotion for Head Lice). Diethanolamine has a monoisotopic molecular weight... Diethylamino hydroxybenzoyl hexyl benzoate Indicated for use as a sunscreen agent. Diethylnorspermine Investigated for use/treatment in renal cell carcinoma, pancreatic cancer, melanoma, and lung cancer. Diethylpropion An appetite suppressant used for the short term treatment of exogenous obesity in addition to calorie restriction. Diethyltryptamine Diethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine. Dimenhydrinate A medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness. Dimethyltryptamine Some people use this compound as a psychedelic inducing agent. Dimetofrine Not Annotated Dinsed Dinsed is a small molecule drug. Dinsed has a monoisotopic molecular weight of 430.03 Da. Dioctyldimonium Not Annotated Diphenhydramine A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. Dipivefrin A prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma. Diprobutine Diprobutine is a small molecule drug. Diprobutine has a monoisotopic molecular weight of 157.18 Da. Distearyldimonium Not Annotated DL-Methylephedrine Used as an antitussive and decongestant . Dobutamine A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. Docarpamine Not Available Dodecyldimethylamine N-oxide Not Available Dodecyltrimethylammonium Not Available Dofetilide A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter. Domiphen Anti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions. Donitriptan Donitriptan is a small molecule drug. The usage of the INN stem '-triptan' in the name indicates that Donitriptan is a sumatriptan derivative serotonin (5HT1) receptor agonist. Donitriptan has a... Dopamine A catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. Dopastatin Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas). Dopexamine Dopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer. DP-b99 Investigated for use/treatment in strokes and traumatic brain injuries. Droxidopa A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease. Dulozafone Dulozafone is a small molecule drug. The usage of the INN stem '-zafone' in the name indicates that Dulozafone is a alozafone derivative. Dulozafone has a monoisotopic molecular weight of... Edetate calcium disodium anhydrous A chelating agent used to treat lead poisoning. Edetic acid A chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias. Edrophonium A cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis. Efaproxiral Not Available Eflucimibe Eflucimibe is a small molecule drug. Eflucimibe has a monoisotopic molecular weight of 469.3 Da. Egtazic acid Egtazic acid is a small molecule drug. Egtazic acid has a monoisotopic molecular weight of 380.14 Da. Eletriptan A triptan used for the treatment of migraines. Elsulfavirine Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact... Eltenac Eltenac is a small molecule drug. The usage of the INN stem '-ac' in the name indicates that Eltenac is a anti-inflammatory agent, ibufenac derivative. Eltenac has a monoisotopic molecular... Embutramide Not Available Emepronium Not Annotated Emixustat Emixustat has been used in trials studying the treatment of Geographic Atrophy, Age-Related Macular Degeneration, and Dry Age-related Macular Degeneration. Emopamil Prevents renal injury after warm & cold ischemia. Enasidenib An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. Encainide A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects. Encaleret Not Available Enobosarm Enobosarm has been used in trials studying the treatment of Stress Urinary Incontinence and Triple Negative Breast Cancer. Enviroxime Enviroxime is a small molecule drug. Enviroxime has a monoisotopic molecular weight of 358.11 Da. Epacadostat Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others. Epanolol Epanolol is an beta blocker. Ephedrine An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Eprotirome Investigated for use/treatment in hyperlipidemia, metabolic disease, and obesity. Ersentilide Ersentilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Ersentilide is a sematilide derivative class III antiarrhythmic. Ersentilide has a monoisotopic... Escitalopram A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). Esmolol A cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension. Etafedrine A beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa. Etersalate Etersalate is a small molecule drug. Etersalate has a monoisotopic molecular weight of 357.12 Da. Ethambutol An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB). Ethanolamine A viscous, hygroscopic amino alcohol with an ammoniacal odor. It is widely distributed in biological tissue and is a component of lecithin. It is used as a surfactant, fluorimetric reagent,... Ethylenediamine Ethylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... Eticyclidine Eticyclidine is a small molecule drug. The usage of the INN stem '-clidine/-clidinium' in the name indicates that Eticyclidine is a muscarinic receptor agonist/antagonist. Eticyclidine has a monoisotopic molecular weight... Etidocaine Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage... Etilefrine An adrenergic agonist primarily of α1 and β1 receptors used as an anti-hypotensive. Etilevodopa Investigated for use/treatment in parkinson's disease. Etryptamine Developed in the 1960's for use as an antidepressant before market withdrawal in 1962. Ezogabine An antiepileptic agent used as an adjuvant treatment of partial-onset seizures. Famprofazone Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan. It is important to note that the drug is metabolized to methamphetamine... Fantofarone Fantofarone is a small molecule drug. Fantofarone has a monoisotopic molecular weight of 550.25 Da. Farudodstat Farudodstat (ASLAN003) is under investigation in clinical trial NCT03451084 (A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia). Fasentin Not Annotated Fedotozine Fedotozine is a small molecule drug. Fedotozine has a monoisotopic molecular weight of 373.23 Da. Felezonexor Felezonexor is a small molecule drug. The usage of the INN stem '-nexor' in the name indicates that Felezonexor is a nuclear export inhibitor. Felezonexor is under investigation in clinical... Fendiline Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. Fenethylline Not Available Fenfluramine Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures. Fenoterol A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. Fenproporex Fenproporex is used as an appetite suppressant, and anti-obesity agent [2]; however, due to substance abuse potential, it is an illicit substance in many countries. In some countries, such as... Fepradinol Not Annotated Ferric ammonium citrate Not Annotated Filaminast Filaminast is a phosphodiesterase 4 inhibitor (PDE4 inhibitor). As such, has potential in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Fingolimod A sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19. Florbetaben F-18 A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment. Florbetapir F-18 A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment. Flumatinib Flumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic. Fluorocholine F-18 A radiopharmaceutical indicated in PET scans of the prostate. Fluorodopa (18F) Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes... Fluoxetine A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. Flupirtine Investigated for use/treatment in fibromyalgia. Flusoxolol Flusoxolol is a small molecule drug. The usage of the INN stem '-olol' in the name indicates that Flusoxolol is a β-adrenoreceptor antagonist. Flusoxolol has a monoisotopic molecular weight of... Flutamide An antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma. Flutemetamol Flutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning). Flutemetamol (18F) A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment. Fluvoxamine A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. Foretinib Foretinib has been used in trials studying the treatment of Cancer, Breast Cancer, Carcinoma, Renal Cell, Recurrent Breast Cancer, and Neoplasms, Head and Neck, among others. Foretinib is an orally... Formoterol An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD. Fosopamine Fosopamine is a small molecule drug. Fosopamine has a monoisotopic molecular weight of 247.06 Da. Fostamatinib A spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment. Frovatriptan A 5-HT1B/1D receptor agonist used to treat migraines. Frunexian Not Available Furosemide A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. Gabapentin An anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. Gadodiamide A gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize lesions and abnormal vascularity. Gadopentetic acid A gadolinium compound used as a contrast agent in MRIs. Gadoxetic acid A gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize the liver. Gallamine Not Annotated Gallamine triethiodide A nondepolarizing nerve blocker used in addition to anesthesia to cause skeletal muscle relaxation. Gallichrome Not Available Gallopamil Gallopamil has been used in trials studying the treatment of Asthma. GED-0507-34-Levo GED-0507-34-Levo is under investigation in clinical trial NCT02808390 (Efficacy and Safety Study of Ged-0507-34-levo for Treatment of UC). Gentian violet cation An antiseptic violet dye used to prevent various infections, including fungal and bacterial infections. Gepefrine Not Annotated Ghavamiol Not Available Gilteritinib An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia. Givinostat A histone deacetylase inhibitor indicated for the treatment of Duchenne Muscular Dystrophy (DMD). Glucoraphanin Glucoraphanin is under investigation in clinical trial NCT01879878 (Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]). Glutamine hydroxamate Not Available Glutathionylspermidine Not Available Glycopyrronium An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia. Golvatinib Golvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck. GSK2256098 GSK2256098 is under investigation in clinical trial NCT02523014 (Vismodegib and FAK Inhibitor GSK2256098 in Treating Patients With Progressive Meningiomas). GW-3965 GW-3965 is a liver X receptor ligand. Heptaminol A cardiac stimulant and vasodilator indicated in the treatment of hemorrhoids and venolymphatic insufficiency. Hexafluronium Used as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations. Hexamethonium A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been... Hexamethylene diamine Not Available Hexoprenaline Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent. Hexylcaine Used as a local anesthetic for surface application, infiltration or nerve block Histamine An ingredient of topical drugs for the relief of joint pain or muscle aches and pains. Histamine glutarimide Histamine glutarimide is under investigation in clinical trial NCT03450434 (XC8 in the Treatment of Patients With Bronchial Asthma). Histidinol Not Available Hydroxyamphetamine An indirectly acting sympathomimetic agent producing mydriasis for diagnostic purposes. Iadademstat Not Annotated Ibopamine A sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Ichthammol Ichthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed... Idalopirdine Idalopirdine has been used in trials studying the treatment of Cognition, Schizophrenia, and Alzheimer's Disease. Idrapril Idrapril is a small molecule drug. The usage of the INN stem '-pril' in the name indicates that Idrapril is a angiotensin-converting enzyme inhibitor. Idrapril has a monoisotopic molecular weight... Idrocilamide Not Annotated Ilomastat Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor. Ilorasertib Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others. Imidocarb Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites. Indatraline Indatraline is a nonselective monoamine reuptake inhibitor. Indenolol Indenolol is a drug of the beta-adrenergic blocker class. Indirubin-3'-monoxime Not Available Indium In-111 satumomab pendetide For diagnosis of extrahepatic malignant cancers Indopan Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention... Inosine pranobex A medication used to treat subacute sclerosing panencephalitis. Iofetamine I-123 Not Annotated Isoetharine For the treatment of asthma, wheezing, and chronic asthmatic bronchitis. Isometheptene A sympathomimetic used to relieve painful spasms in combination with other agents such as caffeine and metamizole. Isoprenaline A catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. Isopropamide A long-acting anticholinergic drug used to relieve symptoms of spastic and painful symptoms of gastrointestinal conditions and symptoms of flu, colds, and related conditions. Isosulfan blue A visual lymphatic imaging agent used during lymphography as an adjunct. Isoxsuprine A beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease. Ivacaftor A cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication. Ivaltinostat Not Annotated Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Lanicemine Lanicemine has been used in trials studying the treatment and basic science of Depression, Major Depressive Disorder, and Treatment Resistant Major Depressive Disorder. Lanopepden Lanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases, Infectious, and Skin Infections, Bacterial. Lauryldimethylbetaine Not Available Lefetamine Lefetamine is a small molecule drug. Lefetamine has a monoisotopic molecular weight of 225.15 Da. Lesogaberan Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others. Levobunolol A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Levobupivacaine A drug used for nerve block and anesthesia. Levocarnitine A quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia. Levodopa A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. Levonordefrin A topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures. Levosalbutamol A beta-2 adrenergic receptor agonist used to treat COPD and asthma. Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Light green SF yellowish Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in... Linerixibat An ileal bile acid transporter (IBAT) inhibitor indicated for the treatment of cholestatic pruritus in adult patients with primary biliary cholangitis. Lisdexamfetamine A central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and moderate to severe eating disorders. Lorlatinib An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. Lumacaftor A protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene. LX-2931 Investigated for use/treatment in rheumatoid arthritis, inflammatory disorders (unspecified), and autoimmune diseases. Malachite Green Not Available Mangafodipir An organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas. Marimastat For the treatment of various cancers Martinostat Martinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer). Mavacamten A myosin inhibitor used to treat obstructive hypertrophic cardiomyopathy. Mavorixafor A CXC chemokine receptor 4 antagonist used to treat WHIM syndrome. MDL72527 Not Available Mebenil An obsolete fungicide used to control various pathogens on cereals and seed potatoes. Mebeverine An antispasmodic used for the symptomatic treatment of stomach pain and spasms associated with irritable bowel syndrome and other gastrointestinal illnesses. Mebrofenin Not Annotated Medifoxamine Medifoxamine was marketed as an atypical antidepressant, with anxiolyitc properties in France, Spain, and Morrocco in the 1990s but was later withdrawn from the market due to it causing cases... Mefenamic acid An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. Mefenorex Not Annotated Melagatran Not Annotated Melatonin An endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement. Melevodopa A methyl ester of levodopa indicated in combination with carbidopa for the treatment of Parkinson's disease. Mephedrone Mephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders. Mephentermine A sympathomimetic agent used in the treatment of hypotension. Mepindolol Mepindolol is a 2-methyl derivative of pindolol. It is a beta blocker. Mepyramine An antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. Mescaline Mescaline is under investigation in clinical trial NCT05933213 (Comparing Mescaline Sodium Enteric-coated Tablets vs Morte-mescaline in the Treatment of Adult Lupus Nephritis). Mesdopetam Mesdopetam is under investigation in clinical trial NCT04435431 (A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia). Metabromsalan Not Annotated Metamfetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity. Metaraminol For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage Methacholine A parasympathomimetic bronchoconstrictor used to diagnose bronchial hyperreactivity in subjects who do not have clinically apparent asthma. Methantheline For the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children. Methaphenilene Methaphenilene is a small molecule drug. Methaphenilene has a monoisotopic molecular weight of 260.13 Da. Methapyrilene Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. Methenamine A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy. Methfuroxam Methfuroxam is under investigation in clinical trial NCT01213407 (Dendritic Cell Cancer Vaccine for High-grade Glioma). Methoxamine An alpha adrenergic agonist used to treat hypotension. Methoxyamine Investigated for use/treatment in cancer/tumors (unspecified). Methoxyphenamine Not Annotated Methylamine Not Available Methylbenactyzium Not Annotated Methyldopa A centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises. Methylenedioxyethamphetamine Not Available Methylnaltrexone A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. Methylone Methylone is under investigation in clinical trial NCT05741710 (A Study to Assess the use of Methylone in the Treatment of PTSD). Metipranolol A beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Metocurine Metocurine is a muscle relaxant. Metocurine iodide For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy. Metoprolol A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction. Mexiletine A class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. Midodrine An alpha-adrenergic agonist used to treat orthostatic hypotension. Midomafetamine Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used... Milameline Milameline is a small molecule drug. Milameline has a monoisotopic molecular weight of 154.11 Da. Milrinone A PDE-III inhibitor with inotropic, lusitropic, and vasodilatory properties used for the short-term treatment of acute decompensated heart failure. Miltefosine An antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type. Mirabegron A beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity. Miramistin ion Miramistin ion is under investigation in clinical trial NCT05561816 (Efficacy and Safety of Dioxidin Versus Miramistin in Superficial Pyoderma). Miransertib Miransertib is under investigation in clinical trial NCT01473095 (Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma). Mirdametinib A kinase inhibitor used to treat neurofibromatosis type 1 in children and adults. MMDA MMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present. Mobocertinib An oral kinase inhibitor targeted against EGFR and used in the treatment of NSCLC with EGFR exon 20 insertion mutations. Mofegiline Mofegiline is a small molecule drug. The usage of the INN stem '-giline' in the name indicates that Mofegiline is a monoamine oxydase (MAO)-inhibitor type B. Mofegiline has a monoisotopic... Molnupiravir An orally bioavailable isopropylester cytidine analog used to treat COVID-19. Moxisylyte According to the WHO, moxisylyte is indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage. The cerebral infarction is characterized by the blockage of the artery either... N-acetylhistamine Not Available N-acetylserotonin Not Available N-Caffeoyltyramine Not Available N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate Not Available N-hydroxyguanidine Not Available N-oleoyldopamine N-oleoyldopamine (OLDA) is an amide of dopamine and oleic acid. N-T-Butylhydroxylamine Not Annotated N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction. N,N'-diphenyl-1,4-phenylenediamine Not Annotated Nadolol A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension. Naftifine An antifungal agent used to treat infections of the Tinea, Trichophyton, and Epidermophyton species. NAP-226-90 Not Available Naphthoquine Naphthoquine is under investigation in clinical trial NCT01930331 (Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO). Naporafenib Naporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With Nras-mutant Melanoma (SEACRAFT-2)). Naratriptan A 5-HT1B/1D receptor agonist used to treat migraines. Navitoclax Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies, among others. Navitoclax is... NCX 701 Investigated for use/treatment in pain (acute or chronic). Nebivolol A beta blocking agent used to treat hypertension and aid in the management of heart failure. Neltenexine Neltenexine is an elastase inhibitor. It may be useful for preventing pulmonary emphysema. Neostigmine A cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone. Nexopamil Nexopamil is a small molecule drug. Nexopamil has a monoisotopic molecular weight of 404.3 Da. Nicarbazin Not Annotated Niclosamide An anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children. Nisoxetine Nisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s. It was originally investigated as an antidepressant but has no current clinical applications aside from being a research... Nolasiban Nolasiban is under investigation in clinical trial NCT03081208 (Phase 3 Placebo Controlled Study of Nolasiban to Improve Pregnancy Rates in Women Undergoing IVF/ICSI). Norelgestromin A progestin used as the progestational component of a transdermal combined hormonal contraceptive, preventing pregnancy primarily through suppression of ovulation. Norepinephrine A sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. Norfenefrine Not Annotated Nortopixantrone Nortopixantrone is a small molecule drug. Nortopixantrone has a monoisotopic molecular weight of 380.2 Da. NP-51 Not Annotated NS-3728 Investigated for use/treatment in anemia (sickle cell) and cancer/tumors (unspecified). NS-8593 Not Annotated NSI-189 NSI-189 is under investigation in clinical trial NCT02695472 (Study of NSI-189 for Major Depressive Disorder). Nylidrin A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders. Obidoxime Not Annotated Octamethylenediamine Not Available Octopamine Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as... Ofornine Ofornine is a small molecule drug. Ofornine has a monoisotopic molecular weight of 281.15 Da. Olaflur A fluoride treatment for patients at risk of dental caries, sensitive teeth, or enamel decalcification. Oleic monoethanolamide Not Available Oleylphosphocholine Not Annotated Ombitasvir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Ondelopran Ondelopran has been used in trials studying the treatment of Alcohol Dependence. OPC-28326 Investigated for use/treatment in peripheral vascular disease and raynaud's disease. Orciprenaline A beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD. Orludodstat Orludodstat is a small molecule drug. The usage of the INN stem '-dodstat' in the name indicates that Orludodstat is a dihydro-orotate dehydrogenase (DHODH) inhibitor. Orludodstat is under investigation in... Orphenadrine A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. Osimertinib A tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma. Otilonium A spasmolytic medication used to treat irritable bowel syndrome (IBS). Oxdralazine Oxdralazine is a small molecule drug. Oxdralazine has a monoisotopic molecular weight of 213.12 Da. Oxethazaine An antacid used to treat gastritis, peptic ulcer disease, heartburn, esophagitis, hiatus hernia, and anorexia. Oxilofrine An amphetamine used to treat a cough associated with inflamed mucosa. Oxprenolol A non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety. Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema. Oxyclozanide Oxyclozanide is a small molecule drug. Oxyclozanide has a monoisotopic molecular weight of 398.88 Da. Oxyfedrine Not Annotated Oxyphenonium For the treatment of visceral spasms Ozenoxacin A quinolone antibiotic used to treat impetigo caused by susceptible bacteria. p-Aminophenol Not Annotated p-Phenylenediamine Not Annotated Padnarsertib Not Annotated Palmidrol A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food... Panobinostat A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents. Parapropamol Parapropamol is a small molecule drug. Parapropamol has a monoisotopic molecular weight of 165.08 Da. Pargyline For the treatment of moderate to severe hypertension. Patent Blue A dye used to label lymphatic vessels, arterial territories, and lymph nodes prior to biopsy in some cancers. Pelcitoclax Pelcitoclax is under investigation in clinical trial NCT04210037 (Study of Combination APG-1252 Plus Paclitaxel in Patients With Relapsed/refractory Small Cell Lung Cancer). Pelitinib Investigated for use/treatment in colorectal cancer and lung cancer. Penbutolol A beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents. Pendetide Pendetide is a small molecule drug. Pendetide has a monoisotopic molecular weight of 741.32 Da. Pentetic acid DTPA is widely used in industry and medicine. As a medical agent, it is approved for its use in medical imaging and for the decorporation of internally deposited radionuclides. It... Pentetreotide A somatostatin receptor inhibitor, available in a kit with Indium-111, used as a contrast agent in the visualization of somatostatin receptor-positive neuroendocrine tumours. Penthienate Not Annotated Perifosine Investigated for use/treatment in solid tumors, multiple myeloma, leukemia (unspecified), lung cancer, and brain cancer. Perindopril An ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction. Pexidartinib An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. PG-530742 Investigated for use/treatment in osteoarthritis. Phenacetin Used principally as an analgesic. Phenaridine Phenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. It was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl. In rat studies,... Phenazopyridine A local anesthetic used for the symptomatic relief of pain, burning, urgency, frequency, and general discomfort caused by lower urinary tract irritations that are a result of infection, trauma, surgery, endoscopic procedures, or the passage of equipment or catheters. Phenethylamine Not Available Phenoxybenzamine An alpha adrenergic antagonist used to treat pheochromocytoma and episodes of hypertension and sweating. Phentermine A sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity. Phenylephrine An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. Phenylpropanolamine A sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy. Phosphocysteamine Not Annotated Phosphorylcolamine Not Available Phthalylsulfathiazole A sulfonamide antibacterial indicated in the treatment of gastrointestinal infections. Phytosphingosine Not Annotated Pilsicainide Pilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation. Pincainide Pincainide is a small molecule drug. The usage of the INN stem '-cain-' in the name indicates that Pincainide is a class I antiarrhythmic, procainamide and lidocaine derivative. Pincainide has... Pindolol A beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation. Pirbuterol A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. Piroctone Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. Recently... Pittsburgh Compound B Pittsburgh Compound B is under investigation in clinical trial NCT01723553 (Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD). Platelet Activating Factor Not Available Platensimycin Not Available Plerixafor A CXCR4 antagonist used in combination with granulocyte-colony stimulating factor to mobilize hematopoietic stem cells to the peripheral blood for collection and autologous transplantation in patients with non-Hodgkin’s lymphoma and multiple myeloma. Plomestane Plomestane is a small molecule drug. The usage of the INN stem '-mestane' in the name indicates that Plomestane is a aromatase inhibitor. Plomestane has a monoisotopic molecular weight of... Poseltinib Poseltinib is under investigation in clinical trial NCT02628028 (A Study of LY3337641 in Rheumatoid Arthritis). Practolol Used in the emergency treatment of cardiac arrhythmias. Pradigastat Pradigastat has been used in trials studying the treatment of Non-alcoholic Fatty Liver Disease (NAFLD). Pralidoxime A cholinesterase reactivator used to treat organophosphate poisoning. Pramiverine Pramiverine is a small molecule drug. The usage of the INN stem '-verine' in the name indicates that Pramiverine is a spasmolytic with a papaverine-like action. Pramiverine has a monoisotopic... Prenalterol Not Annotated Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Prilocaine A local anesthetic used in dental procedures. Procaterol A beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Promethazine A first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness. Propacetamol Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy. Propanidid An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918) Propantheline An antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder. Propranolol A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. Propylhexedrine It is used to provide temporary symptomatic relief of nasal congestion due to colds, allergies and allergic rhinitis. Protokylol Protokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States. Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis. Putrescine Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more... PXS-4728A free base PXS-4728A free base is under investigation in clinical trial NCT05904717 (Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder). Pyroxamide Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others. Pyrrocaine Pyrrocaine is a small molecule drug. The usage of the INN stem '-caine' in the name indicates that Pyrrocaine is a local anaesthetic. Pyrrocaine has a monoisotopic molecular weight of... Quaternium-15 Quaternium-15 is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... Quisinostat Quisinostat has been used in trials studying the treatment of Lymphoma, Neoplasms, Myelodysplastic Syndromes, and Advanced or Refractory Leukemia. R-306465 R306465 has been used in trials studying the treatment of Neoplasms. Racepinephrine A bronchodilator used to treat intermittent asthma. Ractopamine Not Annotated Rafoxanide Rafoxanide is a small molecule drug. Rafoxanide has a monoisotopic molecular weight of 624.82 Da. Razuprotafib Razuprotafib, also known as AKB-9778, is a small-molecule inhibitor restoring Tie2 activation by inhibiting VE-PTP. In investigations against diabetes and COVID-19, razuprotafib is self-administered by patients through subcutaneous injection. Refametinib Investigated for use/treatment in cancer/tumors (unspecified). REP8839 For the treatment of bacterial infections caused by susceptible microorganisms (Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), and Streptococcus pyogenes). Reposal Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia. Reproterol A short-acting β2 adrenoreceptor agonist used to treat various types of asthma including allergic asthma, non-allergic asthma, and exercise-induced asthma. Resminostat Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others. Resorantel Resorantel is a small molecule drug. The usage of the INN stem '-antel' in the name indicates that Resorantel is a anthelminthic. Resorantel has a monoisotopic molecular weight of 306.98... Ribociclib A cyclin-dependent kinase inhibitor used to treat HR+, HER2- breast cancer. Ricolinostat Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer. Risotilide Risotilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Risotilide is a sematilide derivative class III antiarrhythmic. Risotilide has a monoisotopic... Ritobegron Ritobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin... Ritodrine An adrenergic beta agonist used to treat premature labor. Rizatriptan A triptan used to treat migraines with or without aura. Robenacoxib Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs. Roflumilast A selective phosphodiesterase-4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) and to treat skin conditions such as plaque psoriasis and atopic dermatitis. Ropivacaine An amide-type local anesthetic used for local or regional anesthesia during surgery and for short-term management of acute pain. S-23 An androgen receptor modulator. Safinamide A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes. Safingol Safingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. Salicylanilide Not Annotated Salmeterol A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. Sapropterin A cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU). SC-74020 Not Available Scriptaid Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties. Selegiline A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. Semapimod Semapimod has been used in trials studying the treatment of Crohn Disease. Serdemetan Serdemetan has been used in trials studying the treatment of Neoplasms. Serotonin For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product. Sertraline A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. Sevelamer A phosphate binder used to treat hyperphosphatemia. Sibrafiban Sibrafiban is a small molecule drug. The usage of the INN stem '-fiban' in the name indicates that Sibrafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist). Sibrafiban has... Silver sulfadiazine A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns. Sitravatinib Sitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma). Sivopixant Not Available Sodium feredetate Not Annotated Solabegron Investigated for use/treatment in diabetes mellitus type 2, irritable bowel syndrome (IBS), and urinary incontinence. Solimastat Solimastat is a small molecule drug. The usage of the INN stem '-mastat' in the name indicates that Solimastat is a matrix metalloproteinase inhibitor. Solimastat has a monoisotopic molecular weight... Sotalol A methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter. Spermidine Spermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and... Spermine For nutritional supplementation, also for treating dietary shortage or imbalance Sphingosine An amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed) SQ-109 Investigated for use/treatment in bacterial infection, infectious and parasitic disease (unspecified), and tuberculosis. Stirocainide Stirocainide is a small molecule drug. The usage of the INN stem '-cain-' in the name indicates that Stirocainide is a class I antiarrhythmic, procainamide and lidocaine derivative. Stirocainide has... Succinylcholine A depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. Succinylsulfathiazole Not Annotated Sulfacarbamide Sulfacarbamide is a small molecule drug. Sulfacarbamide has a monoisotopic molecular weight of 215.04 Da. Sulfacetamide A sulfonamide used to treat inflammatory ocular conditions and acne vulgaris. Sulfachlorpyridazine A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine. Sulfaclomide Sulfaclomide is a small molecule drug. Sulfaclomide has a monoisotopic molecular weight of 312.04 Da. Sulfaclozine Sulfaclozine is a small molecule drug. Sulfaclozine has a monoisotopic molecular weight of 284.01 Da. Sulfacytine Used orally in the treatment of acute urinary tract infections. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Sulfadimethoxine For use in the treatment of infections. Sulfadoxine A long acting sulfonamide used for the treatment or prevention of malaria. Sulfaethoxypyridazine Not Annotated Sulfaguanidine Sulfaguanidine is a sulfonamide antibiotic with antimicrobial and antibacterial activities. Sulfaisodimidine Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has... Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sulfameter Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. Sulfamethazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Sulfamethoxazole An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. Sulfamethoxypyridazine A sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis. Sulfametopyrazine An antibiotic used in the treatment or prevention of bacterial infections and malaria. Sulfametrole An antibiotic indicated in combination intravenous products for various bacterial infections. Sulfamoxole For the treatment of bacterial infection. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Sulfanitran Not Annotated Sulfaphenazole For the treatment bacterial infections. Sulfaproxyline Sulfaproxyline is a small molecule drug. Sulfaproxyline has a monoisotopic molecular weight of 334.1 Da. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Sulfaquinoxaline Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K... Sulfasymazine Sulfasymazine is a small molecule drug. Sulfasymazine has a monoisotopic molecular weight of 307.11 Da. Sulfathiazole Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. Sulfathiourea Not Annotated Sulfatolamide Not Annotated Sulfatroxazole Sulfatroxazole is a small molecule drug. Sulfatroxazole has a monoisotopic molecular weight of 267.07 Da. Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Suloctidil Not Annotated Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Suzetrigine A sodium channel blocker used to treat moderate to severe acute pain in adults. Synephrine Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer... Tacedinaline Tacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer. Talinolol Talinolol has been investigated for the basic science of Gastrointestinal Motility Disorder. Talopram Talopram is a selective norepinephrine reuptake inhibitor (SNRI) that is structurally similar to citalopram and melitracen. It was researched in the 1960s and 1970s but never marketed. Technetium Tc-99m exametazime A radiopharmaceutical diagnostic agent used as an adjunct for scintigraphy in the detection of altered regional cerebral perfusion in stroke. Technetium Tc-99m mebrofenin A diagnostic radiopharmaceutical agent used during hepatobiliary imaging tests. Teclozan An antiprotozoal agent indicated in the treatment of intestinal amebiasis. Tefinostat Tefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)). Tenamfetamine An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons... Tenitramine Not Annotated Terbutaline A beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor. Teriflunomide A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. Terodiline Not Annotated Tertatolol Tertatolol is a beta blocker. Tetraethylammonium Tetraethylammonium is an experimental drug with no approved indication. Tetramethylammonium Not Available Theodrenaline Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Thiazinam Not Annotated THK-5351 Not Annotated Thonzonium A cationic surfactant used to disperse exudate and cellular debris, as well as enhance the penetration of antimicrobials. Tiapamil Tiapamil is a small molecule drug. Tiapamil has a monoisotopic molecular weight of 555.2 Da. Tiapride A dopamine D2 and D3 receptor antagonist indicated in the treatment of chorea in Huntington's disease, as well as agitation and anxiety in the elderly or with acute or chronic alcoholism. Timolol A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. Tocainide An orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias. Tolpropamine Not Annotated Tolterodine A muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency. Tosedostat Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. Tosedostat is an inhibitor of the... Tosylchloramide A chlorinated disinfectant of the genitals and injured skin. Tramadol A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Tranylcypromine A monoamine oxidase inhibitor used to treat major depressive disorder. Tribromsalan Tribromsalan is a small molecule drug. Tribromsalan has a monoisotopic molecular weight of 446.81 Da. Trichostatin A Not Available Triclocarban An antibacterial agent used in liquid soaps and body washes. Tridihexethyl Used as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus Triethylenetetramine A copper chelating agent used for the management of Wilson's disease in cases where penicillamine therapy is clinically inappropriate. Trimethyltetradecylammonium Not Annotated Tripelennamine A histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold. TRO40303 TRO40303 is under investigation in clinical trial NCT01374321 (Safety and Efficacy Study of TRO40303 for Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute Myocardial Infarction). Trodusquemine Investigated for use/treatment in obesity and diabetes mellitus type 2. Trolamine Trolamine is used as an alkalizing agent, surfactant, and counter-ion in cosmetic and pharmaceutical formulations . It is not considered to be an active pharmacological ingredient and so has no... Trolnitrate Not Annotated Trypanothione Not Available Tryptamine Not Available Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to... Tucidinostat Investigated for use/treatment in cancer/tumors (unspecified). Tulobuterol An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD. Tyramine Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An... Tyramine O-sulfate Not Annotated Ulixertinib Ulixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity . It is currently in clinical trials for the treatment of a wide range of... Upamostat Upamostat has been used in trials studying the treatment of Pancreatic Cancer. Uprosertib Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others. V116517 V116517 is under investigation in clinical trial NCT01688947 (Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)). Vactosertib Vactosertib is under investigation in clinical trial NCT03724851 (Vactosertib in Combination With Pembrolizumab in Metastatic Colorectal or Gastric Cancer). Valethamate An anticholinergic medication used to symptomatically manage conditions involving smooth muscle spasms including spastic constipation, dysmenorrhea, and gastrointestinal tract cramping. Vecabrutinib Vecabrutinib is under investigation in clinical trial NCT03037645 (Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers). Venlafaxine A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder. Verapamil A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. Viminol An opioid analgesic indicated in the treatment of pain. Vismodegib A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. Visometin cation Not Annotated Vorasidenib A isocitrate dehydrogenase type 1 (IDH1) and 2 (IDH2) inhibitor used to treat Grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation. Vorinostat A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. VS-4718 VS-4718 is under investigation in clinical trial NCT02215629 (Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia). WAY-151693 Not Available Xamoterol Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but... Ximelagatran For the treatment of acute deep vein thrombosis. Xylarohydroxamate Not Available Zapnometinib Not Annotated Zinviroxime Zinviroxime is a small molecule drug. Zinviroxime has a monoisotopic molecular weight of 358.11 Da. Zolmitriptan A member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults. ZY19489 Not Annotated Zytron Zytron (DMPA) is under investigation for the treatment and health services research of HIV, Lactation, Contraception, Postpartum Depression, and Immune Cells (Mucosal and Systemic). DMPA has been investigated for the... - Drugs & Drug Targets