4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen. Sensitivity to this... Sensitivity to this compound may be identified with a clinical patch test.
- Primary indication
- 4-(Isopropylamino)diphenylamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.Curator reviewed
- Formula / weight
- C15H18N2 · 226.323 g/mol (avg)
- First approval
- United States, 2012
- Also known as
- Cyzone · IPPD · Nonox ZA
- Code names
- 4010 NA
Resolves to
Clinical / RWD
Structure
InChIKey
OUBMGJOQLXMSNT-UHFFFAOYSA-NSMILESCC(C)NC1=CC=C(NC2=CC=CC=C2)C=C1What you can answer from here — as of September 12, 2026
Which companies are running trials of 4-(Isopropylamino)diphenylamine, in which indications and phases, and which of those programs are still active?
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